Asset profile

exendin-4 Fc fusion (JY09)

Protein / enzyme therapeutic

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Phase 3underway

Evidence outlook · registrational

Type 2 Diabetes: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. The registry's posted readout date (2026-10-01) has passed without a status update. Check News for topline announcements.

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Competitive landscape

110 competitors in this universe: 24 direct rivals (same mechanism and indication), 26 same-class, 60 same-indication; 34 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Exendin-4 Fc Fusion (JY09): this drugPhase 3Protein / enzyme therapeuticGLP-1 receptor
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Lixisenatide (Adlyxin / Lyxumia)ApprovedPeptideGLP-1 receptor
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor
Semaglutide (Wegovy / Ozempic / Rybelsus)ApprovedPeptideGLP-1 receptor
AleniglipronPhase 3Small moleculeGLP-1 receptor
AmycretinPhase 3PeptideGLP-1 receptor, Amylin receptor
Cagrilintide / Semaglutide (CagriSema)Phase 3PeptideAmylin receptor, GLP-1 receptor
CJC-1134-PCPhase 3PeptideGLP-1 receptor
EfpeglenatidePhase 3PeptideGLP-1 receptor
ElecoglipronPhase 3Small moleculeGLP-1 receptor
HDG1901Phase 3Small moleculeGLP-1 receptor
HRS-7535Phase 3Small moleculeGLP-1 receptor
HSK7653Phase 3Small moleculeGLP-1 receptor
IcoSema (Kyinsu)Phase 3PeptideInsulin receptor (basal), GLP-1 receptor

…and 95 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

18 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 1 (3)