Asset profile

repaglinide · Prandin / NovoNorm

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Type 2 Diabetes

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Competitive landscape

62 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Repaglinide (Prandin / NovoNorm): this drugApprovedSmall moleculeSUR1 (short-acting)
Nateglinide (Starlix)ApprovedSmall moleculeSUR1 (short-acting)
Mitiglinide (Glufast)Phase 3Small moleculeSUR1 (short-acting)
AfrezzaApprovedPeptideInsulin receptor (basal), Insulin
Alogliptin (Nesina)ApprovedSmall moleculeDPP-4
Bexagliflozin (Brenzavvy)ApprovedSmall moleculeSGLT2
Canagliflozin (Invokana)ApprovedSmall moleculeSGLT2
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Ertugliflozin (Steglatro)ApprovedSmall moleculeSGLT2
Glipizide (Glucotrol)ApprovedSmall moleculeSulfonylurea receptor (SUR1)
Glyburide (Diabeta / Micronase)ApprovedSmall moleculeSulfonylurea receptor (SUR1)
Insulin Aspart (NovoLog / Fiasp)ApprovedPeptideInsulin receptor
Insulin Degludec (Tresiba)ApprovedPeptideInsulin receptor (basal)
Insulin Detemir (Levemir)ApprovedPeptideInsulin receptor (basal)

…and 47 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
March 2027 (1)
Phase 1TP53 Y220C Mutation, Advanced Solid TumorsRecruiting
Est. primary completion 2027-03 · NCT07372625 · CT.gov ↗
What to watch
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December 2027 (1)
Phase 1/2Locally Advanced Solid Tumor, Metastatic Solid TumorRecruiting
Est. primary completion 2027-12 · NCT05384626 · CT.gov ↗
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2028 (1)
March 2028 (1)
Phase 1Advanced MalignanciesRecruiting
Est. primary completion 2028-03-09 · NCT07340190 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (4)
Phase 1/2 (1)
Phase 1 (35)
Phase 4 (17)
Early phase / not applicable (5)
Used as active comparator (3)