Asset profile

Dapagliflozin · Farxiga / Forxiga

Small molecule

Approvedregulatory verdict

Evidence outlook

Approved — Chronic Kidney Disease, Type 2 Diabetes, Heart Failure

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

Also in development:Atherosclerotic Cardiovascular Disease · Phase 3

How the evidence outlook works ↗

Featured trials

Research

Unlock featured-trial analysis

Research includes the instrumental studies, endpoints, key results, design grades, rationales and source links behind the Outlook.

Upcoming events

(31 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (8)

September 2026 (2)

Phase 3Chronic Kidney Failure in Children and Young AdultsRecruiting

Est. primary completion 2026-09 · NCT05944016 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 1/2Chronic Kidney DiseaseActive not recruiting

Est. primary completion 2026-09-30 · NCT05719714 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

October 2026 (3)

Phase 2Doxorubicin Induced Cardiomyopathy, Breast CancerRecruiting

Est. primary completion 2026-10-01 · NCT06427226 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2/3Type 2 DiabetesActive not recruiting

Est. primary completion 2026-10-18 · NCT07033585 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Type 2 DiabetesActive not recruiting

Est. primary completion 2026-10-30 · NCT07026968 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

November 2026 (1)

Phase 3Atherosclerotic Cardiovascular DiseaseRecruiting

Est. primary completion 2026-11-04 · NCT06772168 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2026 (2)

Phase 2Chronic Kidney DiseaseRecruiting

Est. primary completion 2026-12-31 · NCT06155604 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Heart FailureRecruiting

Est. primary completion 2026-12-31 · NCT06304857 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (10)

January 2027 (1)

Phase 1/2Chronic Kidney DiseaseActive not recruiting

Est. primary completion 2027-01-28 · NCT07678203 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

February 2027 (2)

Phase 2Heart FailureRecruiting

Est. primary completion 2027-02 · NCT06762964 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Chronic Kidney DiseaseActive not recruiting

Est. primary completion 2027-02-18 · NCT06087835 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

May 2027 (2)

Phase 3Chronic Kidney DiseaseNot yet recruiting

Est. primary completion 2027-05-01 · NCT07598864 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2Chronic Kidney DiseaseRecruiting

Est. primary completion 2027-05-24 · NCT07222917 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

July 2027 (1)

Phase 3Chronic Kidney DiseaseEnrolling by invitation

Est. primary completion 2027-07 · NCT05374291 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

October 2027 (1)

Phase 2Kidney Transplant RecipientsRecruiting

Est. primary completion 2027-10-01 · NCT05938712 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2027 (3)

Phase 2Retinal Degeneration, Retinal Diseases, Eye Diseases, Geographic Atrophy, Pathological Conditions, AnatomicalRecruiting

Est. primary completion 2027-12 · NCT07174687 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2Chronic Kidney DiseaseNot yet recruiting

Est. primary completion 2027-12 · NCT06072326 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Chronic Coronary Syndrome, Atrial FibrillationRecruiting

Est. primary completion 2027-12-04 · NCT05852704 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (9)

January 2028 (1)

Phase 2/3Heart FailureNot yet recruiting

Est. primary completion 2028-01-31 · NCT07469722 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

February 2028 (2)

Phase 2Type 1 Diabetes MellitusNot yet recruiting

Est. primary completion 2028-02 · NCT07225465 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Chronic Kidney DiseaseActive not recruiting

Est. primary completion 2028-02-24 · NCT06268873 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

July 2028 (2)

Phase 3Type 2 DiabetesRecruiting

Est. primary completion 2028-07-05 · NCT07662109 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Type 2 DiabetesRecruiting

Est. primary completion 2028-07-14 · NCT07662044 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2028 (1)

Phase 2Heart FailureRecruiting

Est. primary completion 2028-08-31 · NCT07273838 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

September 2028 (1)

Phase 3Heart Transplant Failure, Kidney FailureActive not recruiting

Est. primary completion 2028-09-30 · NCT05321706 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

November 2028 (1)

Phase 2Heart FailureRecruiting

Est. primary completion 2028-11 · NCT07245069 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2028 (1)

Phase 2Atherosclerotic Cardiovascular DiseaseNot yet recruiting

Est. primary completion 2028-12-01 · NCT07741890 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2029 (3)

January 2029 (1)

Phase 3Chronic Kidney DiseaseRecruiting

Est. primary completion 2029-01-15 · NCT07025629 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2029 (2)

Phase 3Heart FailureRecruiting

Est. primary completion 2029-12-17 · NCT06677060 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Chronic Kidney DiseaseRecruiting

Est. primary completion 2029-12-18 · NCT06742723 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2030 (1)

July 2030 (1)

Phase 3Chronic Kidney DiseaseNot yet recruiting

Est. primary completion 2030-07-01 · NCT07624305 · CT.gov ↗

What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.

Competitive landscape

Research

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Research compares assets by shared mechanism and indication, including each competitor's stage in the relevant market.