Asset profile

laroprovstat/rosuvastatin

Small molecule

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Phase 3underway

Evidence outlook · registrational

Atherosclerotic Cardiovascular Disease: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-05-28.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 18 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Laroprovstat / Rosuvastatin: this drugPhase 3Small moleculePCSK9 (laroprovstat component) + HMG-CoA reductase
Alirocumab (Praluent)ApprovedMonoclonal antibodyPCSK9
Bempedoic Acid (Nexletol)ApprovedSmall moleculeAdenosine Triphosphate-Citrate Lyase Inhibitor, ATP citrate lyase
Bempedoic Acid / EzetimibeApprovedSmall moleculeATP citrate lyase (ACLY, bempedoic acid) and NPC1L1 (ezetimibe)
Cangrelor (Kengreal)ApprovedSmall moleculeP2Y12 receptor
Colchicine (cardiovascular) (Lodoco)ApprovedSmall moleculeMicrotubule/inflammasome (tubulin)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Evolocumab (Repatha)ApprovedMonoclonal antibodyPCSK9
Icosapent Ethyl (Vascepa)ApprovedSmall moleculeOmega-3 fatty acid (EPA)
Inclisiran (Leqvio)ApprovedRNA / oligonucleotidePCSK9
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Lomitapide (Juxtapid)ApprovedSmall moleculeMTP
NexlizetApproved——
Olezarsen (Tryngolza)ApprovedRNA / oligonucleotideAPOC3
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
May 2027 (1)
Phase 3Atherosclerotic Cardiovascular DiseaseNot yet recruiting
Est. primary completion 2027-05-28 · NCT07619118 · CT.gov ↗
What to watch
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July 2027 (1)
Phase 3Atherosclerotic Cardiovascular DiseaseRecruiting
Est. primary completion 2027-07-30 · NCT07619131 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 1 (1)