Asset profile

dulaglutide · Trulicity

Peptide

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Approvedregulatory verdict

Evidence outlook

Approved: Atherosclerotic Cardiovascular Disease, Type 2 Diabetes

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

167 competitors in this universe: 24 direct rivals (same mechanism and indication), 26 same-class, 117 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Dulaglutide (Trulicity): this drugApprovedPeptideGLP-1 receptor
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Lixisenatide (Adlyxin / Lyxumia)ApprovedPeptideGLP-1 receptor
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor
Semaglutide (Wegovy / Ozempic / Rybelsus)ApprovedPeptideGLP-1 receptor
AleniglipronPhase 3Small moleculeGLP-1 receptor
AmycretinPhase 3PeptideGLP-1 receptor, Amylin receptor
Cagrilintide / Semaglutide (CagriSema)Phase 3PeptideAmylin receptor, GLP-1 receptor
CJC-1134-PCPhase 3PeptideGLP-1 receptor
EfpeglenatidePhase 3PeptideGLP-1 receptor
ElecoglipronPhase 3Small moleculeGLP-1 receptor
Exendin-4 Fc Fusion (JY09)Phase 3Protein / enzyme therapeuticGLP-1 receptor
HDG1901Phase 3Small moleculeGLP-1 receptor
HRS-7535Phase 3Small moleculeGLP-1 receptor
HSK7653Phase 3Small moleculeGLP-1 receptor
IcoSema (Kyinsu)Phase 3PeptideInsulin receptor (basal), GLP-1 receptor

…and 152 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

18 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 1/2Menstrual Irregularities, Type 1 Diabetes Mellitus, Glucagon-Like Peptide-1 Receptor Agonists, Female Reproductive HealthEnrolling by invitation
Est. primary completion 2026-12 · NCT07319286 · CT.gov ↗
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2027 (3)
April 2027 (1)
Phase 4Type 2 DiabetesNot yet recruiting
Est. primary completion 2027-04 · NCT07537088 · CT.gov ↗
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June 2027 (1)
Phase 2Cystic Fibrosis, Pancreatic Insufficiency, Abnormal Glucose Tolerance, DiabetesRecruiting
Est. primary completion 2027-06-30 · NCT04731272 · CT.gov ↗
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December 2027 (1)
Phase 3Type 2 DiabetesRecruiting
Est. primary completion 2027-12 · NCT06739122 · CT.gov ↗
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2028 (2)
June 2028 (1)
Phase 2Diabetes Mellitus, Type 1, Endothelial DysfunctionRecruiting
Est. primary completion 2028-06-30 · NCT05478707 · CT.gov ↗
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December 2028 (1)
Phase 4Myocardial InjuryRecruiting
Est. primary completion 2028-12-31 · NCT06324461 · CT.gov ↗
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2030 (1)
December 2030 (1)
Phase 2/3Atherosclerotic Cardiovascular DiseaseRecruiting
Est. primary completion 2030-12-01 · NCT07282041 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (25)
Phase 2/3 (2)
Phase 2 (15)
Phase 1/2 (2)
Phase 1 (17)
Phase 4 (17)
Early phase / not applicable (5)
Used as active comparator (24)