Asset profile

MGL-2086

Small molecule

Mechanism not established
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—preclinical

Evidence outlook

No clinical-stage evidence registered

No clinical trials are registered for this drug yet, so there is nothing to grade.

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Competitive landscape

9 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 9 same-indication; 9 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
MGL-2086: this drugNot yet studiedSmall molecule—
Resmetirom (Rezdiffra)ApprovedSmall moleculeThyroid hormone receptor-beta
AramcholPhase 3—Stearoyl-CoA desaturase 1 (SCD1)
DenifanstatPhase 3Small moleculeFatty acid synthase (FASN), FASN
LanifibranorPhase 3Small moleculePeroxisome proliferator-activated receptors (PPARs), PPAR (pan-agonist)
ORMD-0801Phase 3PeptideInsulin receptor (basal)
ALG-055009Phase 2Small molecule—
DA-1241Phase 2Small moleculeFXR
PF-06865571Phase 2—Diacylglycerol acyltransferase 2 (DGAT2)
VK2809Phase 2Small moleculeThyroid hormone receptor-beta
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Upcoming events

No upcoming readouts on record for this asset.

All registered studies

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