Asset profile

orforglipron · Foundayo

Small molecule

Approvedregulatory verdict

Evidence outlook

Approved — Obesity

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

Also in development:Atherosclerotic Cardiovascular Disease · Phase 3Type 2 Diabetes · Phase 3

How the evidence outlook works ↗

Upcoming events

(15 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
November 2026 (1)
Phase 3ObesityActive not recruiting
Est. primary completion 2026-11 · NCT06649045 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (9)
February 2027 (1)
Phase 3ObesityRecruiting
Est. primary completion 2027-02 · NCT06672549 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

May 2027 (1)
Phase 3Type 2 DiabetesNot yet recruiting
Est. primary completion 2027-05 · NCT07613307 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2027 (3)
Phase 3Type 2 DiabetesActive not recruiting
Est. primary completion 2027-08 · NCT06972472 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3ObesityActive not recruiting
Est. primary completion 2027-08 · NCT06972459 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Type 2 DiabetesActive not recruiting
Est. primary completion 2027-08 · NCT06993792 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

September 2027 (3)
Phase 3HypertensionActive not recruiting
Est. primary completion 2027-09 · NCT06948422 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3HypertensionActive not recruiting
Est. primary completion 2027-09 · NCT06952530 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3ObesityActive not recruiting
Est. primary completion 2027-09 · NCT06948435 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2027 (1)
Phase 3ObesityRecruiting
Est. primary completion 2027-12 · NCT06672939 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (3)
March 2028 (1)
Phase 3Urinary Incontinence,StressRecruiting
Est. primary completion 2028-03 · NCT07202884 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

April 2028 (1)
Phase 3OsteoarthritisRecruiting
Est. primary completion 2028-04 · NCT07153471 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

June 2028 (1)
Phase 3Atherosclerotic Cardiovascular DiseaseRecruiting
Est. primary completion 2028-06 · NCT07223593 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2030 (1)
March 2030 (1)
Phase 3Type 2 DiabetesNot yet recruiting
Est. primary completion 2030-03 · NCT07668336 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2031 (1)
August 2031 (1)
Phase 3Atherosclerotic Cardiovascular DiseaseRecruiting
Est. primary completion 2031-08 · NCT07241390 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.

Competitive landscape

Research

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