Asset profile

insulin glargine · Lantus / Toujeo

Peptide

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Approvedregulatory verdict

Evidence outlook

Approved: Type 2 Diabetes

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

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Competitive landscape

80 competitors in this universe: 19 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Insulin Glargine (Lantus / Toujeo): this drugApprovedPeptideInsulin receptor (basal)
AfrezzaApprovedPeptideInsulin receptor (basal), Insulin
Insulin Degludec (Tresiba)ApprovedPeptideInsulin receptor (basal)
Insulin Detemir (Levemir)ApprovedPeptideInsulin receptor (basal)
Insulin Glulisine (Apidra)ApprovedPeptideInsulin receptor (basal)
Insulin Icodec (Awiqli)ApprovedPeptideInsulin receptor (basal)
Insulin Lispro (Humalog)ApprovedPeptideInsulin receptor (basal)
LY2963016 (Basaglar)ApprovedPeptideInsulin receptor (basal)
LY900014 (Lyumjev)ApprovedPeptideInsulin receptor (basal)
SAR341402ApprovedPeptideInsulin receptor (basal)
GZR33Phase 3PeptideInsulin receptor (basal)
IcoSema (Kyinsu)Phase 3PeptideInsulin receptor (basal), GLP-1 receptor
INS068Phase 3PeptideInsulin receptor (basal)
Insulin Efsitora AlfaPhase 3Protein / enzyme therapeuticInsulin receptor (basal)
ORMD-0801Phase 3PeptideInsulin receptor (basal)
THDB0206Phase 3PeptideInsulin receptor (basal)

…and 65 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

11 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(9 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 4Type 1 Diabetes MellitusRecruiting
Est. primary completion 2026-12 · NCT03463564 · CT.gov ↗
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2027 (4)
April 2027 (1)
Phase 2Type 1 Diabetes MellitusActive not recruiting
Est. primary completion 2027-04-28 · NCT06111586 · CT.gov ↗
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June 2027 (2)
Phase 4Type 2 DiabetesNot yet recruiting
Est. primary completion 2027-06-30 · NCT07173712 · CT.gov ↗
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Phase 4Type 2 DiabetesRecruiting
Est. primary completion 2027-06-30 · NCT07307235 · CT.gov ↗
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December 2027 (1)
Phase 4Pregestational Diabetes, PregnancyRecruiting
Est. primary completion 2027-12-01 · NCT07224893 · CT.gov ↗
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2028 (3)
February 2028 (1)
Phase 4Steroid-Induced Diabetes, Steroid-Induced Hyperglycemia, DiabetesEnrolling by invitation
Est. primary completion 2028-02-09 · NCT07117240 · CT.gov ↗
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May 2028 (1)
Early phase / not applicableSafety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite AthletesEnrolling by invitation
Est. primary completion 2028-05-01 · NCT07568574 · CT.gov ↗
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June 2028 (1)
Early phase / not applicableType 2 DiabetesNot yet recruiting
Est. primary completion 2028-06 · NCT07652528 · CT.gov ↗
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2029 (1)
December 2029 (1)
Phase 4Gestational Diabetes Mellitus, Pregnancy, High RiskRecruiting
Est. primary completion 2029-12 · NCT06445946 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (165)
Phase 2/3 (1)
Phase 2 (27)
Phase 1/2 (1)
Phase 1 (49)
Phase 4 (228)
Early phase / not applicable (65)
Used as active comparator (140)
Appears in other studies (129)