Asset profile

OLOMAX

Small molecule

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Evidence outlook · lead readout

NCT01764295 · Hypertension, Dyslipidemia

The completed lead evidence is positive, with design limits that temper confidence; the rationale below says which.

NCT01764295: The study was randomized and triple-blinded, with active and placebo comparator groups and an estimated enrollment of 150 participants. Its primary measures were changes in LDL cholesterol and diastolic blood pressure, and because the registry provides no results, it is not possible to determine whether either primary endpoint was met.

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Competitive landscape

62 competitors in this universe: 1 direct rival (same mechanism and indication), 1 same-class, 60 same-indication; 18 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
OLOMAX: this drugPhase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
CJ-30061Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
CJ-30060Phase 3Small moleculeAngiotensin II receptor / Calcium channel / HMG-CoA reductase
Alirocumab (Praluent)ApprovedMonoclonal antibodyPCSK9
Bempedoic Acid (Nexletol)ApprovedSmall moleculeAdenosine Triphosphate-Citrate Lyase Inhibitor, ATP citrate lyase
Bempedoic Acid / EzetimibeApprovedSmall moleculeATP citrate lyase (ACLY, bempedoic acid) and NPC1L1 (ezetimibe)
Cangrelor (Kengreal)ApprovedSmall moleculeP2Y12 receptor
Colchicine (cardiovascular) (Lodoco)ApprovedSmall moleculeMicrotubule/inflammasome (tubulin)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Evolocumab (Repatha)ApprovedMonoclonal antibodyPCSK9
Icosapent Ethyl (Vascepa)ApprovedSmall moleculeOmega-3 fatty acid (EPA)
Inclisiran (Leqvio)ApprovedRNA / oligonucleotidePCSK9
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Lomitapide (Juxtapid)ApprovedSmall moleculeMTP
NexlizetApproved——

…and 47 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.