Asset profile

Saxagliptin · Onglyza

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Type 2 Diabetes

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

79 competitors in this universe: 19 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Saxagliptin (Onglyza): this drugApprovedSmall moleculeDPP-4
Alogliptin (Nesina)ApprovedSmall moleculeDPP-4
Linagliptin (Tradjenta)ApprovedSmall moleculeDPP-4
Sitagliptin (Januvia)ApprovedSmall moleculeDPP-4
Anagliptin (Suiny)Phase 3Small moleculeDPP-4
DBPR108Phase 3Small moleculeDPP-4
Evogliptin (Suganon)Phase 3Small moleculeDPP-4
Gemigliptin (Zemiglo)Phase 3Small moleculeDPP-4
GosogliptinPhase 3Small moleculeDPP-4
HenagliflozinPhase 3Small moleculeSodium-glucose cotransporter 2 (SGLT2), DPP-4
MP-513Phase 3Small moleculeDPP-4
Omarigliptin (Marizev)Phase 3Small moleculeDPP-4
SP2086Phase 3Small moleculeDPP-4
SYR-472Phase 3Small moleculeDPP-4
Teneligliptin (Tenelia)Phase 3Small moleculeDPP-4
Trelagliptin (Zafatek)Phase 3Small moleculeDPP-4

…and 64 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

13 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
October 2026 (1)
Phase 2/3Type 2 DiabetesActive not recruiting
Est. primary completion 2026-10-18 · NCT07033585 · CT.gov ↗
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2027 (1)
February 2027 (1)
Early phase / not applicableType 2 DiabetesRecruiting
Est. primary completion 2027-02-28 · NCT02969798 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (42)
Phase 2/3 (3)
Phase 2 (5)
Phase 1 (21)
Phase 4 (36)
Early phase / not applicable (6)
Used as active comparator (2)