Asset profile
Cofrogliptin
Small molecule
Evidence outlook
Early-stage evidence only
Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
79 competitors in this universe: 19 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 79 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| Cofrogliptin: this drug | Not yet studied | Small molecule | DPP-4 | ||
| Alogliptin (Nesina) | Approved | Small molecule | DPP-4 | ||
| Linagliptin (Tradjenta) | Approved | Small molecule | DPP-4 | ||
| Saxagliptin (Onglyza) | Approved | Small molecule | DPP-4 | ||
| Sitagliptin (Januvia) | Approved | Small molecule | DPP-4 | ||
| Anagliptin (Suiny) | Phase 3 | Small molecule | DPP-4 | ||
| DBPR108 | Phase 3 | Small molecule | DPP-4 | ||
| Evogliptin (Suganon) | Phase 3 | Small molecule | DPP-4 | ||
| Gemigliptin (Zemiglo) | Phase 3 | Small molecule | DPP-4 | ||
| Gosogliptin | Phase 3 | Small molecule | DPP-4 | ||
| Henagliflozin | Phase 3 | Small molecule | Sodium-glucose cotransporter 2 (SGLT2), DPP-4 | ||
| MP-513 | Phase 3 | Small molecule | DPP-4 | ||
| Omarigliptin (Marizev) | Phase 3 | Small molecule | DPP-4 | ||
| SP2086 | Phase 3 | Small molecule | DPP-4 | ||
| SYR-472 | Phase 3 | Small molecule | DPP-4 | ||
| Teneligliptin (Tenelia) | Phase 3 | Small molecule | DPP-4 |
…and 64 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Compare head-to-head
13 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.
Upcoming events
(3 total)
Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
2026 (1)
October 2026 (1)
What to watch
2027 (2)
June 2027 (1)
What to watch
December 2027 (1)
What to watch
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.