Asset profile

BCMA-CD19 compound CAR (cCAR) T cells

Cell therapy

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Systemic Lupus Erythematosus · Phase 1

How the evidence outlook works ↗

Competitive landscape

112 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 110 same-indication; 96 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
BCMA-CD19 Compound CAR (cCAR) T Cells: this drugPhase 1Cell therapyBCMA / CD19
AZD0120Phase 3Cell therapyBCMA / CD19
ICG318Phase 2Cell therapyBCMA / CD19
AnifrolumabApprovedMonoclonal antibodyType I interferon receptor, Type I interferon receptor subunit 1 (IFNAR1)
Avacopan (Tavneos)ApprovedSmall moleculeComplement C5a receptor 1 (C5aR1/CD88)
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
Belimumab (GSK1550188)ApprovedMonoclonal antibodyBAFF / BLyS (B-lymphocyte stimulator), BAFF (BLyS)
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA

…and 97 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 1 (3)
Appears in other studies (3)