Asset profile

RAPA-201

Cell therapy

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Weakdesign only

Evidence outlook · no controlled comparison

NCT04176380 · Relapsed, Refractory Multiple Myeloma

The lead study is single-arm or otherwise uncontrolled, so it produced no formal comparison against a control. This tier describes the design, not an outcome.

NCT04176380: This was a small, single-arm, open-label study with no control group and no blinding, so while most patients achieved a response, there is no comparator to show how much of that response is attributable to RAPA-201 itself.

Also in development:Non-Small Cell Lung Cancer · Phase 1/2

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Competitive landscape

120 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 120 same-indication; 111 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
RAPA-201: this drugPhase 2Cell therapyRapamycin-resistant autologous T-cell therapy
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
BortezomibApprovedSmall moleculeProteasome
BrigatinibApprovedSmall moleculeALK
CapmatinibApprovedSmall moleculeMET
CarfilzomibApprovedSmall moleculeProteasome

…and 105 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2029 (1)
March 2029 (1)
Phase 2Malignant Melanoma With Metastasis, Malignant Melanoma, Malignant Melanoma Stage IIIc, Malignant Melanoma Stage IVNot yet recruiting
Est. primary completion 2029-03-01 · NCT06708455 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1/2 (1)