Asset profile

IBI3003

Multispecific antibody

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Phase 3underway

Evidence outlook · registrational

Multiple Myeloma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2029-05-31.

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Competitive landscape

64 competitors in this universe: 4 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 23 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
IBI3003: this drugPhase 3Multispecific antibodyGPRC5D x BCMA x CD3
RamantamigPhase 3Multispecific antibodyGPRC5D x BCMA x CD3
QLS4131Phase 2Multispecific antibodyGPRC5D x BCMA x CD3
MBS314Phase 1/2—GPRC5D x BCMA x CD3
SIM0500Phase 1Multispecific antibodyGPRC5D x BCMA x CD3
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
IxazomibApprovedSmall moleculeProteasome

…and 49 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
October 2026 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2026-10-31 · NCT06083207 · CT.gov ↗
What to watch
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December 2026 (1)
Phase 2Multiple MyelomaNot yet recruiting
Est. primary completion 2026-12-31 · NCT07764861 · CT.gov ↗
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2027 (1)
June 2027 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2027-06-30 · NCT07336472 · CT.gov ↗
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2029 (1)
May 2029 (1)
Phase 3Multiple MyelomaRecruiting
Est. primary completion 2029-05-31 · NCT07623798 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.