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Hrain anti-BCMA CAR-T

Cell therapy

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

61 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 60 same-indication; 51 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Hrain Anti-BCMA CAR-T: this drugPhase 2Cell therapyCAR-T cell therapy
JY232Phase 1Cell therapyCAR-T cell therapy
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
IxazomibApprovedSmall moleculeProteasome
LenalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Thalidomide Analog
LinvoseltamabApprovedMultispecific antibodyBCMA x CD3
Melphalan FlufenamideApprovedSmall moleculeDNA (alkylation), delivered via aminopeptidase-mediated intracellular activation

…and 46 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

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Upcoming events

(27 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (4)
December 2026 (4)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2026-12 · NCT06793449 · CT.gov ↗
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Phase 1SLE (Systemic Lupus), Systemic Sclerosis, ANCA Associated Vasculitis, Idiopathic Inflammatory Myopathies, Sjogren's Syndrome …Recruiting
Est. primary completion 2026-12-31 · NCT06548607 · CT.gov ↗
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Phase 1Non-Hodgkin Lymphoma, B-cellRecruiting
Est. primary completion 2026-12-31 · NCT06446128 · CT.gov ↗
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Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2026-12-31 · NCT04271644 · CT.gov ↗
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2027 (16)
January 2027 (1)
Phase 1SLE, Systemic Sclerosis, IIM, NMOSD, MS, MG, ANCA Associated Vasculitis (AAV)Recruiting
Est. primary completion 2027-01-01 · NCT06775912 · CT.gov ↗
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February 2027 (2)
Phase 1UCRecruiting
Est. primary completion 2027-02-04 · NCT07435779 · CT.gov ↗
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Phase 1Multiple MyelomaNot yet recruiting
Est. primary completion 2027-02-28 · NCT06913192 · CT.gov ↗
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March 2027 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2027-03 · NCT06880393 · CT.gov ↗
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April 2027 (1)
Phase 1Relapsed or Refractory Plasma Cell NeoplasmsRecruiting
Est. primary completion 2027-04-01 · NCT07519187 · CT.gov ↗
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May 2027 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2027-05-20 · NCT06976437 · CT.gov ↗
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June 2027 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2027-06-30 · NCT07085559 · CT.gov ↗
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July 2027 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2027-07-31 · NCT07489534 · CT.gov ↗
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August 2027 (4)
Phase 1Idiopathic Inflammatory Myopathies(IIM), Immune Thrombocytopenia(ITP), Systemic Lupus Erythematosus(SLE)Recruiting
Est. primary completion 2027-08 · NCT07174843 · CT.gov ↗
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Phase 2Multiple MyelomaRecruiting
Est. primary completion 2027-08-01 · NCT07106736 · CT.gov ↗
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Phase 2Multiple MyelomaRecruiting
Est. primary completion 2027-08-01 · NCT07106684 · CT.gov ↗
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Phase 2Multiple MyelomaRecruiting
Est. primary completion 2027-08-01 · NCT07106710 · CT.gov ↗
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October 2027 (2)
Phase 1/2Relapsed/Refractory Warm Antibody Autoimmune Hemolytic AnemiaNot yet recruiting
Est. primary completion 2027-10-31 · NCT07324889 · CT.gov ↗
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Early phase / not applicableMultiple MyelomaRecruiting
Est. primary completion 2027-10-31 · NCT07359014 · CT.gov ↗
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December 2027 (2)
Phase 1Graves' DiseaseRecruiting
Est. primary completion 2027-12 · NCT07261345 · CT.gov ↗
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Phase 1Multiple MyelomaRecruiting
Est. primary completion 2027-12-12 · NCT06732232 · CT.gov ↗
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2028 (6)
February 2028 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2028-02-01 · NCT07477912 · CT.gov ↗
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March 2028 (3)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-03-01 · NCT07377435 · CT.gov ↗
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Phase 1/2Ultra High Risk mm (uhr-mm), 18-70 Years Old, Suitable for ASCT. And Meet Any of the Following uhr-mm Definitions …Recruiting
Est. primary completion 2028-03-02 · NCT07109323 · CT.gov ↗
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Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-03-10 · NCT07200089 · CT.gov ↗
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April 2028 (1)
Phase 2Multiple MyelomaNot yet recruiting
Est. primary completion 2028-04-30 · NCT06963866 · CT.gov ↗
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July 2028 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-07-30 · NCT07139509 · CT.gov ↗
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2035 (1)
December 2035 (1)
Phase 1SLE - Systemic Lupus ErythematosusNot yet recruiting
Est. primary completion 2035-12-31 · NCT07266337 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (14)
Phase 1/2 (11)
Phase 1 (32)
Early phase / not applicable (4)
Appears in other studies (13)