Asset profile

Ciltacabtagene autoleucel

Cell therapy

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Approvedregulatory verdict

Evidence outlook

Approved: Multiple Myeloma

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Weak signal

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Competitive landscape

92 competitors in this universe: 32 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ciltacabtagene Autoleucel: this drugApprovedCell therapyBCMA
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
Idecabtagene VicleucelApprovedCell therapyBCMA
Anitocabtagene AutoleucelPhase 3Cell therapyBCMA
Equecabtagene AutoleucelPhase 3Cell therapyBCMA
HRC0202Phase 2Cell therapyBCMA
PHE885Phase 2Cell therapyBCMA
AZD4045Phase 1/2Cell therapyBCMA
BCMA CAR-NK (Hrain)Phase 1/2Cell therapyBCMA
BCMA CAR-NK (Shenzhen Pregene Biopharma)Phase 1/2Cell therapyBCMA
BCMA-CART (Bioray Laboratories)Phase 1/2Cell therapyBCMA
BCMA-Targeted Prime CAR-T Cells (Chongqing Precision Biotech)Phase 1/2Cell therapyBCMA
GSK2857914Phase 1/2Monoclonal antibodyBCMA
Pamlectabart TismanitinPhase 1/2Adc (anti-bcma Antibody-targeted Amanitin Conjugate)BCMA
SENL103Phase 1/2Cell therapyBCMA
Trovocabtagene Autoleucel (C-CAR088)Phase 1/2Cell therapyBCMA

…and 77 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(14 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (5)
January 2027 (1)
Phase 1Extramedullary MyelomaActive not recruiting
Est. primary completion 2027-01 · NCT05666700 · CT.gov ↗
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February 2027 (1)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2027-02-26 · NCT04133636 · CT.gov ↗
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June 2027 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2027-06-30 · NCT06623630 · CT.gov ↗
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July 2027 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2027-07-01 · NCT07093554 · CT.gov ↗
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August 2027 (1)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2027-08-26 · NCT06550895 · CT.gov ↗
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2028 (3)
March 2028 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-03-10 · NCT07200089 · CT.gov ↗
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April 2028 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2028-04-12 · NCT07149857 · CT.gov ↗
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August 2028 (1)
Phase 1Multiple MyelomaNot yet recruiting
Est. primary completion 2028-08-01 · NCT07725406 · CT.gov ↗
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2029 (1)
February 2029 (1)
Phase 3Multiple MyelomaActive not recruiting
Est. primary completion 2029-02-14 · NCT04923893 · CT.gov ↗
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2030 (1)
September 2030 (1)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2030-09-02 · NCT06577025 · CT.gov ↗
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2031 (1)
August 2031 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2031-08-15 · NCT06940297 · CT.gov ↗
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2032 (1)
September 2032 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2032-09-30 · NCT06574126 · CT.gov ↗
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2033 (1)
June 2033 (1)
Phase 3Multiple MyelomaActive not recruiting
Est. primary completion 2033-06 · NCT05257083 · CT.gov ↗
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2037 (1)
July 2037 (1)
Phase 4Multiple MyelomaRecruiting
Est. primary completion 2037-07-29 · NCT05201781 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (3)
Phase 2 (9)
Phase 1/2 (1)
Phase 1 (5)
Phase 4 (1)
Appears in other studies (2)