Asset profile

Ixazomib

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Multiple Myeloma

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

63 competitors in this universe: 3 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ixazomib: this drugApprovedSmall moleculeProteasome
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
TQB3602Phase 1Small moleculeProteasome
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
LenalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Thalidomide Analog
LinvoseltamabApprovedMultispecific antibodyBCMA x CD3
Melphalan FlufenamideApprovedSmall moleculeDNA (alkylation), delivered via aminopeptidase-mediated intracellular activation
Melphalan Hydrochloride (Evomela)ApprovedSmall moleculeDNA (guanine N7 position)

…and 48 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(11 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2Myeloma, MultipleActive not recruiting
Est. primary completion 2026-12 · NCT04009109 · CT.gov ↗
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2027 (6)
March 2027 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2027-03-31 · NCT04068597 · CT.gov ↗
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April 2027 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2027-04 · NCT02343042 · CT.gov ↗
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July 2027 (1)
Phase 1Relapsing Remitting Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary Progressive Multiple SclerosisRecruiting
Est. primary completion 2027-07-31 · NCT03783416 · CT.gov ↗
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September 2027 (1)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2027-09-01 · NCT04790474 · CT.gov ↗
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October 2027 (1)
Phase 2Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaActive not recruiting
Est. primary completion 2027-10-30 · NCT03763162 · CT.gov ↗
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December 2027 (1)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2027-12-31 · NCT03376672 · CT.gov ↗
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2028 (2)
January 2028 (1)
Phase 2Multiple MyelomaNot yet recruiting
Est. primary completion 2028-01-01 · NCT06744894 · CT.gov ↗
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June 2028 (1)
Phase 1Recurrent AL Amyloidosis, Refractory AL AmyloidosisActive not recruiting
Est. primary completion 2028-06-30 · NCT04847453 · CT.gov ↗
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2029 (1)
March 2029 (1)
Phase 2Kaposi Sarcoma, SkinRecruiting
Est. primary completion 2029-03-15 · NCT04305691 · CT.gov ↗
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2030 (1)
January 2030 (1)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2030-01-01 · NCT04998786 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (12)
Phase 2 (65)
Phase 1/2 (31)
Phase 1 (33)
Phase 4 (6)
Early phase / not applicable (1)
Used as active comparator (2)
Appears in other studies (2)