Asset profile

Cemsidomide

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

How the evidence outlook works ↗

Competitive landscape

67 competitors in this universe: 7 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 52 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Cemsidomide: this drugPhase 2Small moleculeCereblon E3 ubiquitin-ligase
LenalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Thalidomide Analog
PomalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Cereblon (CRBN)
ThalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase
IberdomidePhase 3Small moleculeCereblon E3 ubiquitin-ligase
MezigdomidePhase 3Small moleculeCereblon E3 ubiquitin-ligase
ICP-490Phase 1/2Small moleculeCereblon E3 ubiquitin-ligase
TQB3820Phase 1Small moleculeCereblon E3 ubiquitin-ligase
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3

…and 52 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (1)
December 2028 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-12 · NCT07280013 · CT.gov ↗
What to watch
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2030 (1)
March 2030 (1)
Phase 2Multiple MyelomaRecruiting
Est. primary completion 2030-03 · NCT07284758 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.