Asset profile

Elotuzumab

Monoclonal antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Multiple Myeloma

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Elotuzumab: this drugApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
IxazomibApprovedSmall moleculeProteasome
LenalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Thalidomide Analog
LinvoseltamabApprovedMultispecific antibodyBCMA x CD3
Melphalan FlufenamideApprovedSmall moleculeDNA (alkylation), delivered via aminopeptidase-mediated intracellular activation
Melphalan Hydrochloride (Evomela)ApprovedSmall moleculeDNA (guanine N7 position)
MotixafortideApprovedPeptideCXCR4

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(12 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (4)
November 2026 (2)
Phase 1Multiple MyelomaActive not recruiting
Est. primary completion 2026-11 · NCT05560399 · CT.gov ↗
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Phase 1/2Multiple MyelomaActive not recruiting
Est. primary completion 2026-11-30 · NCT03989414 · CT.gov ↗
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December 2026 (2)
Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2026-12 · NCT02718833 · CT.gov ↗
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Phase 1Multiple MyelomaActive not recruiting
Est. primary completion 2026-12-31 · NCT05981209 · CT.gov ↗
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2027 (5)
April 2027 (3)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2027-04 · NCT02343042 · CT.gov ↗
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Phase 2Multiple MyelomaActive not recruiting
Est. primary completion 2027-04-01 · NCT04835129 · CT.gov ↗
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Phase 2Hematopoietic Cell Transplantation Recipient, Plasma Cell MyelomaActive not recruiting
Est. primary completion 2027-04-30 · NCT02420860 · CT.gov ↗
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December 2027 (2)
Phase 3Multiple MyelomaActive not recruiting
Est. primary completion 2027-12 · NCT06158841 · CT.gov ↗
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Phase 2Myelofibrosis Transformation in Essential Thrombocythemia, Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase, Primary MyelofibrosisActive not recruiting
Est. primary completion 2027-12-31 · NCT04517851 · CT.gov ↗
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2029 (2)
August 2029 (1)
Phase 3Multiple MyelomaActive not recruiting
Est. primary completion 2029-08 · NCT03948035 · CT.gov ↗
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December 2029 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2029-12-31 · NCT06518551 · CT.gov ↗
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2031 (1)
April 2031 (1)
Phase 1/2Multiple MyelomaRecruiting
Est. primary completion 2031-04-01 · NCT06785415 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (8)
Phase 2 (33)
Phase 1/2 (6)
Phase 1 (10)
Used as active comparator (8)