Asset profile

Arlocabtagene autoleucel

Cell therapy

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Phase 3underway

Evidence outlook · registrational

Multiple Myeloma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-12-30.

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Competitive landscape

66 competitors in this universe: 6 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 23 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Arlocabtagene Autoleucel: this drugPhase 3Cell therapyGPRC5D
AZD0305Phase 1/2Antibody–drug conjugateGPRC5D
CT071Phase 1/2Cell therapyGPRC5D
OriCAR-017Phase 1/2Cell therapyGPRC5D
CAR-GPRC5D (RD118, IASO Biotherapeutics)Phase 1Cell therapyGPRC5D
JNJ-87562761Phase 1Not DisclosedGPRC5D
SAR446523Phase 1Biologic (subtype unspecified)GPRC5D
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA

…and 51 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
December 2027 (1)
Phase 3Multiple MyelomaRecruiting
Est. primary completion 2027-12-30 · NCT06615479 · CT.gov ↗
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2028 (1)
August 2028 (1)
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-08-01 · NCT06121843 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.