Asset profile

ICG318

Cell therapy

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Crohn's Disease · Phase 1/2Ulcerative Colitis · Phase 1/2

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Competitive landscape

135 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 133 same-indication; 89 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
ICG318: this drugPhase 2Cell therapyBCMA / CD19
AZD0120Phase 3Cell therapyBCMA / CD19
BCMA-CD19 Compound CAR (cCAR) T CellsPhase 1Cell therapyBCMA / CD19
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha
Adalimumab-Bwwd (Hadlima)Approved—TNF-alpha
Adalimumab-Fkjp (Hulio)Approved—TNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
AnifrolumabApprovedMonoclonal antibodyType I interferon receptor, Type I interferon receptor subunit 1 (IFNAR1)
Avacopan (Tavneos)ApprovedSmall moleculeComplement C5a receptor 1 (C5aR1/CD88)

…and 120 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
December 2027 (1)
Phase 1Inflammatory MyopathyRecruiting
Est. primary completion 2027-12-31 · NCT07715136 · CT.gov ↗
What to watch
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2028 (2)
April 2028 (1)
Phase 1/2Crohn's DiseaseNot yet recruiting
Est. primary completion 2028-04-07 · NCT07544160 · CT.gov ↗
What to watch
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December 2028 (1)
Phase 2Systemic Lupus ErythematosusRecruiting
Est. primary completion 2028-12 · NCT07328581 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Phase 1/2 (1)
Phase 1 (1)