Asset profile
Methylprednisolone
Small molecule
Approved / Phase 4Undisclosed / early pipelineGlucocorticoid receptor agonistNo featureable registry evidence📍 1 UK trial recruiting · UK Hub ↗
Approvedregulatory verdict
Evidence outlook
Approved: Asthma, Crohn's Disease, Ulcerative Colitis
Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.
This drug's registrational program predates the public trial registry, so its Featured trials section is empty by necessity, not by omission.
Featured evidence outside covered markets:NCT00004759 · Spinal Cord Injury · Phase 3 · completed · ungraded
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
145 competitors in this universe: 1 direct rival (same mechanism and indication), 1 same-class, 143 same-indication.
Unlock with Research ↗
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| Methylprednisolone: this drug | Approved | Small molecule | Glucocorticoid receptor agonist | ||
| Budesonide (Pulmicort) | Approved | Small molecule | Glucocorticoid receptor agonist | ||
| Desoximetasone (Topicort Spray) | Approved | Small molecule | Glucocorticoid receptor agonist | ||
| Adalimumab (Humira) | Approved | Monoclonal antibody | TNF-alpha | ||
| Adalimumab-Aacf (Idacio) | Approved | — | TNF-alpha | ||
| Adalimumab-Aaty (Yuflyma) | Approved | — | TNF-alpha | ||
| Adalimumab-Adaz (Hyrimoz) | Approved | — | TNF-alpha | ||
| Adalimumab-Adbm (Cyltezo) | Approved | Monoclonal antibody | TNF-alpha | ||
| Adalimumab-Afzb (Abrilada) | Approved | — | TNF-alpha | ||
| Adalimumab-Aqvh (Yusimry) | Approved | — | TNF-alpha | ||
| Adalimumab-Atto (Amjevita) | Approved | — | TNF-alpha | ||
| Adalimumab-Bwwd (Hadlima) | Approved | — | TNF-alpha | ||
| Adalimumab-Fkjp (Hulio) | Approved | — | TNF-alpha | ||
| Adalimumab-Ryvk (Simlandi) | Approved | — | TNF-alpha | ||
| Albuterol (Armstrong Albuterol HFA) | Approved | Small molecule | Beta-2 adrenergic receptor | ||
| Albuterol / Budesonide (Airsupra) | Approved | Combination | Beta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor |
…and 130 more. Research shows the complete landscape.
Research
Unlock with Research ↗Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Upcoming events
(93 total)
Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
2026 (9)
October 2026 (1)
Phase 4Lupus or SLE, Interstitial Lung Disease, Systemic Lupus ErythematosusRecruiting
Est. primary completion 2026-10-25 · NCT07077486 · CT.gov ↗
What to watch
November 2026 (4)
Phase 2Dysphagia, Laryngeal EdemaRecruiting
Est. primary completion 2026-11-30 · NCT06670521 · CT.gov ↗
What to watch
Phase 2Mandible Fracture, Edema Face, Pain Management, Corticosteroid InjectionRecruiting
Est. primary completion 2026-11-30 · NCT07208799 · CT.gov ↗
What to watch
Phase 4Stroke, Intracerebral Hemorrhage Lobar, Methylprednisolone, SurgeryNot yet recruiting
Est. primary completion 2026-11-30 · NCT06921616 · CT.gov ↗
What to watch
Phase 4Stroke, Intracerebral Hemorrhage Basal Ganglia, Methylprednisolone, SurgeryNot yet recruiting
Est. primary completion 2026-11-30 · NCT06924983 · CT.gov ↗
What to watch
December 2026 (4)
Phase 4Adhesive Capsulitis, Frozen Shoulder, Shoulder FrozenRecruiting
Est. primary completion 2026-12 · NCT02283996 · CT.gov ↗
What to watch
Phase 2Blastic Plasmacytoid Dendritic Cell NeoplasmRecruiting
Est. primary completion 2026-12-31 · NCT04216524 · CT.gov ↗
What to watch
Phase 3Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, BackRecruiting
Est. primary completion 2026-12-31 · NCT05058287 · CT.gov ↗
What to watch
Phase 4Multiple MyelomaRecruiting
Est. primary completion 2026-12-31 · NCT07101445 · CT.gov ↗
What to watch
2027 (35)
January 2027 (6)
Early phase / not applicablePostimplantation Syndrome, Myocardial Injury, MACE, MortalityNot yet recruiting
Est. primary completion 2027-01 · NCT07328906 · CT.gov ↗
What to watch
Phase 2Headaches Associated With Subarachnoid Hemorrhage (SAH)Recruiting
Est. primary completion 2027-01-01 · NCT07054801 · CT.gov ↗
What to watch
Phase 2Fanconi Anemia, Severe Aplastic Anemia, Myelodysplastic Syndromes, T Cell Receptor Alpha/Beta Depletion, Telomere Biology Disorder …Recruiting
Est. primary completion 2027-01-01 · NCT03579875 · CT.gov ↗
What to watch
Early phase / not applicableIdiopathic Pulmonary FibrosisRecruiting
Est. primary completion 2027-01-01 · NCT05842681 · CT.gov ↗
What to watch
Phase 2Plasma Cell Myeloma RefractoryRecruiting
Est. primary completion 2027-01-08 · NCT06356571 · CT.gov ↗
What to watch
Phase 3Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical TrialRecruiting
Est. primary completion 2027-01-31 · NCT05139849 · CT.gov ↗
What to watch
February 2027 (2)
March 2027 (2)
April 2027 (2)
Phase 1Multiple Myeloma in Relapse, Multiple Myeloma, RefractoryRecruiting
Est. primary completion 2027-04-01 · NCT06225310 · CT.gov ↗
What to watch
Phase 2B Acute Lymphoblastic Leukemia, B Lymphoblastic LymphomaActive not recruiting
Est. primary completion 2027-04-01 · NCT05303792 · CT.gov ↗
What to watch
May 2027 (1)
Phase 4Total Knee ArthroplastyRecruiting
Est. primary completion 2027-05-30 · NCT05097976 · CT.gov ↗
What to watch
June 2027 (5)
Phase 2Foot Injuries and Disorders, Ankle Injuries and Disorders, Achilles Tendon InjuryRecruiting
Est. primary completion 2027-06 · NCT06780202 · CT.gov ↗
What to watch
Phase 2Acute Graft-versus-host Disease, Allogeneic Bone Marrow Transplantation, Adverse EffectsRecruiting
Est. primary completion 2027-06-01 · NCT06936566 · CT.gov ↗
What to watch
Phase 3Erythema MultiformeNot yet recruiting
Est. primary completion 2027-06-01 · NCT06266221 · CT.gov ↗
What to watch
Phase 3Adenovirus Infections, HumanNot yet recruiting
Est. primary completion 2027-06-30 · NCT07152600 · CT.gov ↗
What to watch
Phase 4Neuromyelitis Optica Spectrum Disorder AttackRecruiting
Est. primary completion 2027-06-30 · NCT07410039 · CT.gov ↗
What to watch
July 2027 (2)
Phase 1Thyroid Eye Disease, Graves Ophthalmopathy, Graves OrbitopathyNot yet recruiting
Est. primary completion 2027-07-30 · NCT07762105 · CT.gov ↗
What to watch
Phase 1/2Cranial Nerve Disorder, Head and Neck Carcinoma, Oropharyngeal CarcinomaRecruiting
Est. primary completion 2027-07-31 · NCT04151082 · CT.gov ↗
What to watch
August 2027 (1)
Phase 4Unruptured Intracranial Aneurysms, Cerebrovascular Event, Hemorrhagic Stroke, Methylprednisolone, Flow DiverterNot yet recruiting
Est. primary completion 2027-08-31 · NCT07353749 · CT.gov ↗
What to watch
September 2027 (3)
Phase 2Total Knee Replacement, Knee ArthroplastyRecruiting
Est. primary completion 2027-09 · NCT05736549 · CT.gov ↗
What to watch
Phase 2Total Knee Replacement, Knee ArthroplastyRecruiting
Est. primary completion 2027-09 · NCT05279092 · CT.gov ↗
What to watch
Phase 1/2Crohn's DiseaseRecruiting
Est. primary completion 2027-09-30 · NCT04224558 · CT.gov ↗
What to watch
October 2027 (3)
Phase 1/2Amyotrophic Lateral SclerosisRecruiting
Est. primary completion 2027-10-15 · NCT07287397 · CT.gov ↗
What to watch
Phase 1/2X-Linked Myotubular MyopathyRecruiting
Est. primary completion 2027-10-31 · NCT07052929 · CT.gov ↗
What to watch
November 2027 (2)
December 2027 (6)
Phase 3Optic NeuritisRecruiting
Est. primary completion 2027-12 · NCT07623668 · CT.gov ↗
What to watch
Phase 2GVHD, Acute, Stem Cell Transplant ComplicationsRecruiting
Est. primary completion 2027-12-30 · NCT07509749 · CT.gov ↗
What to watch
Phase 2Ischemia Stroke, Thrombectomy, Large Vessel OcclusionRecruiting
Est. primary completion 2027-12-31 · NCT07516522 · CT.gov ↗
What to watch
Phase 3Achilles Tendinopathy (AT)Recruiting
Est. primary completion 2027-12-31 · NCT07650396 · CT.gov ↗
What to watch
Phase 3Acute Ischemic StrokeRecruiting
Est. primary completion 2027-12-31 · NCT07141303 · CT.gov ↗
What to watch
Early phase / not applicableBiliary Atresia, Cholangitis, Anti-Bacterial AgentsRecruiting
Est. primary completion 2027-12-31 · NCT05925309 · CT.gov ↗
What to watch
2028 (22)
January 2028 (1)
Phase 2Thyroid-Associated OphthalmopathyRecruiting
Est. primary completion 2028-01 · NCT04936854 · CT.gov ↗
What to watch
March 2028 (3)
Phase 3Myocarditis AcuteRecruiting
Est. primary completion 2028-03 · NCT05150704 · CT.gov ↗
What to watch
Phase 2IgA Nephropathy (IgAN)Recruiting
Est. primary completion 2028-03-02 · NCT06676579 · CT.gov ↗
What to watch
Phase 1/2Extranodal NK T Cell Lymphoma, Hemophagocytic Lymphohistiocytosis (HLH)Recruiting
Est. primary completion 2028-03-31 · NCT07525466 · CT.gov ↗
What to watch
April 2028 (2)
June 2028 (3)
Phase 2Paraneoplastic Sensory NeuronopathyRecruiting
Est. primary completion 2028-06 · NCT06373211 · CT.gov ↗
What to watch
Phase 2Lupus NephritisRecruiting
Est. primary completion 2028-06-15 · NCT05039619 · CT.gov ↗
What to watch
Phase 2/3Brain Metastases From Solid TumorsNot yet recruiting
Est. primary completion 2028-06-30 · NCT07542288 · CT.gov ↗
What to watch
August 2028 (2)
September 2028 (2)
October 2028 (1)
Phase 2Crohn's DiseaseRecruiting
Est. primary completion 2028-10 · NCT03219359 · CT.gov ↗
What to watch
November 2028 (4)
Early phase / not applicableMigraine Disorders, Medication Overuse Headache, Greater Occipital Nerve BlockNot yet recruiting
Est. primary completion 2028-11-01 · NCT07568496 · CT.gov ↗
What to watch
Phase 3PsittacosisNot yet recruiting
Est. primary completion 2028-11-30 · NCT07352865 · CT.gov ↗
What to watch
Phase 3InfluenzaNot yet recruiting
Est. primary completion 2028-11-30 · NCT07351500 · CT.gov ↗
What to watch
December 2028 (4)
Early phase / not applicableIschemic Stroke, AcuteNot yet recruiting
Est. primary completion 2028-12 · NCT07175649 · CT.gov ↗
What to watch
Early phase / not applicableImmune Checkpoint Inhibitor-Related Pneumonitis, Drug-Related Side Effects and Adverse Reactions, NeoplasmsNot yet recruiting
Est. primary completion 2028-12 · NCT07554885 · CT.gov ↗
What to watch
Phase 2Multiple SclerosisRecruiting
Est. primary completion 2028-12-31 · NCT02784210 · CT.gov ↗
What to watch
Phase 2Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic LeukemiaRecruiting
Est. primary completion 2028-12-31 · NCT06317662 · CT.gov ↗
What to watch
2029 (14)
January 2029 (3)
Phase 3Acute Ischemic StrokeNot yet recruiting
Est. primary completion 2029-01 · NCT06870448 · CT.gov ↗
What to watch
Phase 4Orthopedic SurgeriesEnrolling by invitation
Est. primary completion 2029-01 · NCT03661645 · CT.gov ↗
What to watch
Phase 4Traumatic Brain InjuryRecruiting
Est. primary completion 2029-01-31 · NCT07180277 · CT.gov ↗
What to watch
February 2029 (1)
Phase 2Neuroendocrine Cell Hyperplasia of InfancyRecruiting
Est. primary completion 2029-02-28 · NCT06471556 · CT.gov ↗
What to watch
March 2029 (1)
Phase 3HepatectomyRecruiting
Est. primary completion 2029-03-27 · NCT07507643 · CT.gov ↗
What to watch
June 2029 (1)
Phase 2Aplastic Anemia, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Previously Treated Myelodysplastic SyndromeRecruiting
Est. primary completion 2029-06-30 · NCT01624805 · CT.gov ↗
What to watch
July 2029 (2)
August 2029 (1)
Phase 2/3Kidney Transplant RejectionRecruiting
Est. primary completion 2029-08-15 · NCT07412470 · CT.gov ↗
What to watch
September 2029 (1)
Phase 4Adrenal InsufficiencyNot yet recruiting
Est. primary completion 2029-09-01 · NCT07703098 · CT.gov ↗
What to watch
October 2029 (1)
Phase 2Non-hodgkin LymphomaNot yet recruiting
Est. primary completion 2029-10-01 · NCT07763210 · CT.gov ↗
What to watch
November 2029 (1)
Phase 1/2Frontotemporal DementiaActive not recruiting
Est. primary completion 2029-11-30 · NCT04408625 · CT.gov ↗
What to watch
December 2029 (2)
Phase 4Ulcerative ColitisRecruiting
Est. primary completion 2029-12 · NCT07258771 · CT.gov ↗
What to watch
Phase 4Back Pain Lower Back, Neck Pain, Radiculopathy Multiple Sites, Spinal Stenosis Cervicothoracic Region, Spinal Stenosis Lumbar …Recruiting
Est. primary completion 2029-12 · NCT07762170 · CT.gov ↗
What to watch
2030 (7)
January 2030 (1)
Phase 1/2Lysosomal Diseases, Gangliosidosis, GM1Recruiting
Est. primary completion 2030-01-01 · NCT03952637 · CT.gov ↗
What to watch
June 2030 (2)
Phase 3Rejection; Transplant, Kidney, Rejection; Transplant, PancreasRecruiting
Est. primary completion 2030-06 · NCT06474273 · CT.gov ↗
What to watch
Phase 2Melanoma Stage III, Melanoma Stage IV, Skin Cancer Stage III, Skin Cancer Stage IV, Drug-Induced Colitis, Drug Toxicity …Active not recruiting
Est. primary completion 2030-06-30 · NCT04305145 · CT.gov ↗
What to watch
August 2030 (2)
September 2030 (1)
Phase 4ACL Surgery, Pain ManagementRecruiting
Est. primary completion 2030-09 · NCT07158476 · CT.gov ↗
What to watch
October 2030 (1)
Phase 3Plasma Cell MyelomaActive not recruiting
Est. primary completion 2030-10-14 · NCT04270409 · CT.gov ↗
What to watch
2031 (4)
March 2031 (1)
Phase 1/2Parkinson DiseaseActive not recruiting
Est. primary completion 2031-03-31 · NCT04127578 · CT.gov ↗
What to watch
April 2031 (1)
Phase 3STEMI - ST Elevation Myocardial InfarctionRecruiting
Est. primary completion 2031-04-20 · NCT07478003 · CT.gov ↗
What to watch
August 2031 (1)
Phase 4ACL ReconstructionNot yet recruiting
Est. primary completion 2031-08 · NCT07605923 · CT.gov ↗
What to watch
December 2031 (1)
Phase 3Lupus Nephritis, Systemic Lupus Erythematosus (SLE)Recruiting
Est. primary completion 2031-12 · NCT04702256 · CT.gov ↗
What to watch
2032 (1)
December 2032 (1)
Phase 1/2CTNNB1 Neurodevelopmental SyndromeRecruiting
Est. primary completion 2032-12-31 · NCT07270549 · CT.gov ↗
What to watch
2035 (1)
September 2035 (1)
Phase 2/3Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma, Stage IV T Lymphoblastic Leukemia/Lymphoma …Not yet recruiting
Est. primary completion 2035-09-01 · NCT07072585 · CT.gov ↗
What to watch
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.