Asset profile

WIN378

Monoclonal antibody

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Chronic Obstructive Pulmonary Disease · Phase 2

How the evidence outlook works ↗

Competitive landscape

100 competitors in this universe: 5 direct rivals (same mechanism and indication), 1 same-class, 94 same-indication; 76 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
WIN378: this drugPhase 2Monoclonal antibodyTSLP
Tezepelumab (Tezspire)ApprovedMonoclonal antibodyTSLP, Thymic stromal lymphopoietin (TSLP), ligand-neutralizing
Tezepelumab (APFS)ApprovedMonoclonal antibodyTSLP
CM326Phase 3Monoclonal antibodyTSLP
GSK5784283Phase 3Monoclonal antibodyTSLP
AZD8630Phase 2—TSLP
BSI-045BPhase 2Monoclonal antibodyTSLP
Aclidinium Bromide (Tudorza Pressair)ApprovedSmall moleculeMuscarinic acetylcholine receptor (M3)
Aclidinium Bromide / Formoterol Fumarate (Duaklir Pressair)ApprovedSmall moleculeMuscarinic acetylcholine receptor (M3), Beta-2 adrenergic receptor
Albuterol (Armstrong Albuterol HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol / Budesonide (Airsupra)ApprovedCombinationBeta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
Albuterol HFA (Armstrong's)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol HFA (Proventil HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Armstrong)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Provenetil-HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
AminophyllineApprovedSmall moleculePhosphodiesterase (multi-subtype)

…and 85 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
July 2027 (1)
Phase 2AsthmaActive not recruiting
Est. primary completion 2027-07 · NCT07120503 · CT.gov ↗
What to watch
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December 2027 (1)
Phase 2Chronic Obstructive Pulmonary DiseaseRecruiting
Est. primary completion 2027-12-17 · NCT07646587 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1 (1)