Asset profile

tozorakimab

Monoclonal antibody

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Phase 3underway

Evidence outlook · registrational

Chronic Obstructive Pulmonary Disease: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2028-12-29.

Also in development:Asthma · Phase 2

How the evidence outlook works ↗

Competitive landscape

95 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 93 same-indication; 46 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Tozorakimab: this drugPhase 3Monoclonal antibodyIL-33
ItepekimabPhase 3Monoclonal antibodyIL-33
GSK3862995Phase 1Monoclonal antibodyIL-33
Aclidinium Bromide (Tudorza Pressair)ApprovedSmall moleculeMuscarinic acetylcholine receptor (M3)
Aclidinium Bromide / Formoterol Fumarate (Duaklir Pressair)ApprovedSmall moleculeMuscarinic acetylcholine receptor (M3), Beta-2 adrenergic receptor
Albuterol (Armstrong Albuterol HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol / Budesonide (Airsupra)ApprovedCombinationBeta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
Albuterol HFA (Armstrong's)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol HFA (Proventil HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Armstrong)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Provenetil-HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
AminophyllineApprovedSmall moleculePhosphodiesterase (multi-subtype)
Beclomethasone (QVAR)ApprovedSmall moleculeGlucocorticoid receptor
Beclomethasone Dipropionate / Formoterol Fumarate / GlycopyrrolateApprovedSmall moleculeGlucocorticoid receptor / Beta-2 adrenergic receptor / Muscarinic M3 receptor (ICS/LABA/LAMA triple combination)
Benralizumab (Fasenra)ApprovedMonoclonal antibodyIL-5 receptor alpha, IL-5 receptor alpha (IL-5Rα / CD125); Fc region additionally engages FcγRIIIa on NK cells (ADCC), IL-5 receptor alpha (IL5RA) on eosinophils/basophils
Budesonide (Pulmicort)ApprovedSmall moleculeGlucocorticoid receptor agonist

…and 80 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
June 2027 (1)
Phase 2AsthmaRecruiting
Est. primary completion 2027-06-07 · NCT06932263 · CT.gov ↗
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November 2027 (1)
Phase 3Viral Lung Infection and Acute Respiratory FailureRecruiting
Est. primary completion 2027-11-04 · NCT05624450 · CT.gov ↗
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2028 (1)
December 2028 (1)
Phase 3Chronic Obstructive Pulmonary DiseaseRecruiting
Est. primary completion 2028-12-29 · NCT07566195 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (6)
Phase 2 (6)
Phase 1 (4)