Asset profile

tezepelumab · Tezspire

Monoclonal antibody

Approvedregulatory verdict

Evidence outlook

Approved — Asthma

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2AsthmaActive not recruiting
Est. primary completion 2026-12 · NCT06189742 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (2)
June 2027 (1)
Phase 3AsthmaActive not recruiting
Est. primary completion 2027-06-25 · NCT06473779 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2027 (1)
Phase 3AsthmaRecruiting
Est. primary completion 2027-08-07 · NCT07363642 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (2)
May 2028 (1)
Phase 3AsthmaRecruiting
Est. primary completion 2028-05-31 · NCT06023589 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2028 (1)
Phase 3AsthmaNot yet recruiting
Est. primary completion 2028-12 · NCT07302516 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2029 (3)
March 2029 (2)
Phase 3Chronic Obstructive Pulmonary Disease (COPD)Recruiting
Est. primary completion 2029-03-13 · NCT06883305 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3Chronic Obstructive Pulmonary Disease (COPD)Recruiting
Est. primary completion 2029-03-13 · NCT06878261 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2029 (1)
Phase 3AsthmaNot yet recruiting
Est. primary completion 2029-08-18 · NCT07013123 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.

Competitive landscape

Research

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