Asset profile

PBF-680

Unknown / undisclosed

Phase 2Adenosine A1 receptorNo recent registered activity
Partialsignal

Evidence outlook · lead readout

NCT03774290 · Asthma

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT03774290: This was a randomized, quadruple-blind, placebo-controlled study of 107 participants, using trough FEV1—a lung-function surrogate—as its primary endpoint. Because the registry does not report whether the primary endpoint was met, the trial provides well-designed but currently incomplete evidence.

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