Asset profile

tilrekimig

Multispecific antibody

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Phase 3underway

Evidence outlook · registrational

Asthma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2029-06-12.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 38 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Tilrekimig: this drugPhase 3Multispecific antibodyIL-4/IL-13/TSLP
Albuterol (Armstrong Albuterol HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol / Budesonide (Airsupra)ApprovedCombinationBeta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
Albuterol HFA (Armstrong's)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol HFA (Proventil HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Armstrong)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Provenetil-HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
AminophyllineApprovedSmall moleculePhosphodiesterase (multi-subtype)
Beclomethasone (QVAR)ApprovedSmall moleculeGlucocorticoid receptor
Beclomethasone Dipropionate / Formoterol Fumarate / GlycopyrrolateApprovedSmall moleculeGlucocorticoid receptor / Beta-2 adrenergic receptor / Muscarinic M3 receptor (ICS/LABA/LAMA triple combination)
Benralizumab (Fasenra)ApprovedMonoclonal antibodyIL-5 receptor alpha, IL-5 receptor alpha (IL-5Rα / CD125); Fc region additionally engages FcγRIIIa on NK cells (ADCC), IL-5 receptor alpha (IL5RA) on eosinophils/basophils
Budesonide (Pulmicort)ApprovedSmall moleculeGlucocorticoid receptor agonist
Budesonide / Formoterol Fumarate (SYMBICORT)ApprovedCombinationGlucocorticoid receptor; Beta-2 adrenergic receptor
Budesonide / Glycopyrrolate / Formoterol Fumarate (Breztri Aerosphere)ApprovedSmall moleculeGlucocorticoid receptor; Muscarinic M3; Beta-2 adrenergic
Ciclesonide (Alvesco)ApprovedSmall moleculeGlucocorticoid receptor
DepemokimabApprovedMonoclonal antibodyIL-5

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
October 2026 (1)
Phase 2Atopic DermatitisRecruiting
Est. primary completion 2026-10-19 · NCT05995964 · CT.gov ↗
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2027 (2)
February 2027 (1)
Phase 1HealthyRecruiting
Est. primary completion 2027-02-11 · NCT07792941 · CT.gov ↗
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March 2027 (1)
Phase 2AsthmaRecruiting
Est. primary completion 2027-03-08 · NCT06977581 · CT.gov ↗
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2028 (2)
March 2028 (1)
Phase 3Atopic DermatitisRecruiting
Est. primary completion 2028-03-10 · NCT07765888 · CT.gov ↗
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August 2028 (1)
Phase 3Atopic DermatitisNot yet recruiting
Est. primary completion 2028-08-29 · NCT07783425 · CT.gov ↗
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2029 (1)
June 2029 (1)
Phase 3AsthmaNot yet recruiting
Est. primary completion 2029-06-12 · NCT07772921 · CT.gov ↗
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2030 (1)
October 2030 (1)
Phase 2/3Moderate to Severe Chronic Obstructive Pulmonary DiseaseRecruiting
Est. primary completion 2030-10-24 · NCT07363694 · CT.gov ↗
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2034 (1)
May 2034 (1)
Phase 3Moderate to Severe Chronic Obstructive Pulmonary DiseaseNot yet recruiting
Est. primary completion 2034-05-12 · NCT07839884 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (4)
Phase 2/3 (1)
Phase 2 (2)
Phase 1 (3)