Approved regulatory verdict
Evidence outlook
Approved: Psoriasis, Crohn's Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ulcerative Colitis
Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.
track record: Reliable signal
How the evidence outlook works ↗
Featured trials The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Crohn's Disease · approved · Featured evidence · 3 Psoriasis · approved · Featured evidence · 2 Ulcerative Colitis · approved · Featured evidence · 2 Rheumatoid Arthritis · approved · Featured evidence · 1 approved Featured evidence · 3
Competitive landscape 209 competitors in this universe: 27 direct rivals (same mechanism and indication), 0 same-class, 182 same-indication.
…and 194 more. Research shows the complete landscape.
Research Unlock the full comparison Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Unlock with Research ↗ Compare head-to-head
21 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.
Upcoming events (37 total) Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
2026 (6) October 2026 (2) Phase 1 Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8, Clinical Stage IA Cutaneous Melanoma AJCC v8 … Recruiting
Est. primary completion 2026-10-31 ·
NCT03819296 ·
CT.gov ↗ What to watch Phase 4 Crohn's Disease Recruiting
Est. primary completion 2026-10-31 ·
NCT05043870 ·
CT.gov ↗ What to watch November 2026 (1) Phase 4 Crohn's Disease Recruiting
Est. primary completion 2026-11 ·
NCT05906576 ·
CT.gov ↗ What to watch December 2026 (3) Early phase / not applicable Crohn's Disease Active not recruiting
Est. primary completion 2026-12 ·
NCT06839820 ·
CT.gov ↗ What to watch Phase 2 Acute Pancreatitis Recruiting
Est. primary completion 2026-12-15 ·
NCT03684278 ·
CT.gov ↗ What to watch Early phase / not applicable Crohn's Disease Recruiting
Est. primary completion 2026-12-31 ·
NCT06064864 ·
CT.gov ↗ What to watch 2027 (10) January 2027 (1) Phase 3 Sarcoidosis Active not recruiting
Est. primary completion 2027-01-12 ·
NCT05689879 ·
CT.gov ↗ What to watch March 2027 (2) Phase 1/2 Glaucoma Following Surgery Recruiting
Est. primary completion 2027-03-01 ·
NCT05180994 ·
CT.gov ↗ What to watch Phase 2/3 Crohn's Disease Recruiting
Est. primary completion 2027-03-31 ·
NCT05660746 ·
CT.gov ↗ What to watch May 2027 (1) Phase 2 Ulcerative Colitis Not yet recruiting
Est. primary completion 2027-05-31 ·
NCT07297069 ·
CT.gov ↗ What to watch June 2027 (1) Phase 2 Metastatic Melanoma Active not recruiting
Est. primary completion 2027-06-30 ·
NCT05034536 ·
CT.gov ↗ What to watch July 2027 (2) Phase 2 Relapsing Polychondritis Recruiting
Est. primary completion 2027-07 ·
NCT06941376 ·
CT.gov ↗ What to watch Phase 4 Crohn's Disease Recruiting
Est. primary completion 2027-07-30 ·
NCT05928039 ·
CT.gov ↗ What to watch December 2027 (3) Early phase / not applicable Takayasu Arteritis Recruiting
Est. primary completion 2027-12-15 ·
NCT07491913 ·
CT.gov ↗ What to watch Phase 2 Cytokine Release Syndrome, Recurrent Multiple Myeloma, Refractory Multiple Myeloma Recruiting
Est. primary completion 2027-12-31 ·
NCT07657312 ·
CT.gov ↗ What to watch Early phase / not applicable Checkpoint Inhibitor, Pilot Study, Diabetes Melletus Not yet recruiting
Est. primary completion 2027-12-31 ·
NCT07257068 ·
CT.gov ↗ What to watch 2028 (13) January 2028 (1) Phase 2 Rheumatic Disease Recruiting
Est. primary completion 2028-01 ·
NCT07138898 ·
CT.gov ↗ What to watch February 2028 (1) Early phase / not applicable Crohn's Disease Recruiting
Est. primary completion 2028-02-13 ·
NCT07470502 ·
CT.gov ↗ What to watch March 2028 (3) Phase 2 Sjogren Syndrome, Sjogren Syndrome With Keratoconjunctivitis, Dry Eye Disease (DED) Not yet recruiting
Est. primary completion 2028-03 ·
NCT07671222 ·
CT.gov ↗ What to watch Phase 3 Rheumatoid Arthritis Recruiting
Est. primary completion 2028-03 ·
NCT03414502 ·
CT.gov ↗ What to watch Phase 4 Schizophrenia Recruiting
Est. primary completion 2028-03 ·
NCT05823532 ·
CT.gov ↗ What to watch April 2028 (2) Phase 2 Crohn's Disease Recruiting
Est. primary completion 2028-04-30 ·
NCT06453317 ·
CT.gov ↗ What to watch Phase 3 Ulcerative Colitis Not yet recruiting
Est. primary completion 2028-04-30 ·
NCT06614387 ·
CT.gov ↗ What to watch June 2028 (1) Phase 1/2 Aneurysm, Stroke, Vasculitis, Tumor Necrosis Factor-alpha Recruiting
Est. primary completion 2028-06 ·
NCT02638701 ·
CT.gov ↗ What to watch July 2028 (1) Early phase / not applicable Cardiac Arrest (CA), Post Cardiac Arrest Syndrome Active not recruiting
Est. primary completion 2028-07-31 ·
NCT07176754 ·
CT.gov ↗ What to watch August 2028 (1) Phase 2 Depressive Disorder, Major, Inflammation Recruiting
Est. primary completion 2028-08-31 ·
NCT06136546 ·
CT.gov ↗ What to watch September 2028 (1) Early phase / not applicable Crohn's Disease Active not recruiting
Est. primary completion 2028-09-01 ·
NCT07149441 ·
CT.gov ↗ What to watch November 2028 (1) Early phase / not applicable Crohn's Disease Not yet recruiting
Est. primary completion 2028-11-30 ·
NCT07424040 ·
CT.gov ↗ What to watch December 2028 (1) Phase 4 Crohn's Disease Recruiting
Est. primary completion 2028-12-31 ·
NCT07510191 ·
CT.gov ↗ What to watch 2029 (4) January 2029 (1) Phase 4 Acute Kidney Injury, Acute Interstitial Nephritis Recruiting
Est. primary completion 2029-01-15 ·
NCT07683975 ·
CT.gov ↗ What to watch March 2029 (2) Phase 4 Crohn's Disease Not yet recruiting
Est. primary completion 2029-03-31 ·
NCT07415473 ·
CT.gov ↗ What to watch Phase 4 Crohn's Disease Not yet recruiting
Est. primary completion 2029-03-31 ·
NCT07417696 ·
CT.gov ↗ What to watch October 2029 (1) Early phase / not applicable Crohn's Disease Recruiting
Est. primary completion 2029-10-01 ·
NCT07314606 ·
CT.gov ↗ What to watch 2030 (4) April 2030 (1) Early phase / not applicable Crohn's Disease Not yet recruiting
Est. primary completion 2030-04-01 ·
NCT05584228 ·
CT.gov ↗ What to watch June 2030 (3) Phase 4 Psoriasis Not yet recruiting
Est. primary completion 2030-06-01 ·
NCT07352566 ·
CT.gov ↗ What to watch Phase 4 Ulcerative Colitis Not yet recruiting
Est. primary completion 2030-06-01 ·
NCT07576452 ·
CT.gov ↗ What to watch Phase 2 Melanoma Stage III, Melanoma Stage IV, Skin Cancer Stage III, Skin Cancer Stage IV, Drug-Induced Colitis, Drug Toxicity … Active not recruiting
Est. primary completion 2030-06-30 ·
NCT04305145 ·
CT.gov ↗ What to watch See the full readout calendar ↗
All registered studies Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.
All indications (310) Crohn's Disease (86) Ulcerative Colitis (59) Rheumatoid Arthritis (51) Psoriasis (22) Psoriatic Arthritis (9) Other / comorbidity (126)
Phase 3 (91) Phase 2/3 (8) Phase 2 (50) Phase 1/2 (11) Phase 1 (17) Phase 4 (92) Early phase / not applicable (41) Used as active comparator (21) Appears in other studies (21)