Asset profile

certolizumab pegol · Cimzia

Antibody fragment

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Approvedregulatory verdict

Evidence outlook

Approved: Psoriasis, Crohn's Disease, Rheumatoid Arthritis, Psoriatic Arthritis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

178 competitors in this universe: 26 direct rivals (same mechanism and indication), 1 same-class, 151 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Certolizumab Pegol (Cimzia): this drugApprovedAntibody fragmentTNF-alpha
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha
Adalimumab-Bwwd (Hadlima)Approved—TNF-alpha
Adalimumab-Fkjp (Hulio)Approved—TNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
CT-P13 (Inflectra / Remsima)ApprovedMonoclonal antibodyTNF-alpha
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Golimumab (Simponi)ApprovedMonoclonal antibodyTNF-alpha
Infliximab (Remicade)ApprovedMonoclonal antibodyTNF-alpha

…and 163 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(6 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
December 2027 (2)
Phase 2High Risk Pregnancy, Pregnancy Complications, Antiphospholipid Syndrome in Pregnancy, Lupus Anticoagulant DisorderRecruiting
Est. primary completion 2027-12 · NCT03152058 · CT.gov ↗
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Early phase / not applicableTakayasu ArteritisRecruiting
Est. primary completion 2027-12-15 · NCT07491913 · CT.gov ↗
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2028 (2)
January 2028 (1)
Phase 2Rheumatic DiseaseRecruiting
Est. primary completion 2028-01 · NCT07138898 · CT.gov ↗
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March 2028 (1)
Phase 3Rheumatoid ArthritisRecruiting
Est. primary completion 2028-03 · NCT03414502 · CT.gov ↗
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2029 (1)
April 2029 (1)
Phase 3Recurrent Unexplained Implantation FailureRecruiting
Est. primary completion 2029-04 · NCT05930613 · CT.gov ↗
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2030 (1)
June 2030 (1)
Phase 4PsoriasisNot yet recruiting
Est. primary completion 2030-06-01 · NCT07352566 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (57)
Phase 2/3 (2)
Phase 2 (15)
Phase 1 (12)
Phase 4 (18)
Early phase / not applicable (3)
Used as active comparator (1)
Appears in other studies (1)