Asset profile

MT-201

Multispecific antibody

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Ulcerative Colitis · Phase 2

How the evidence outlook works ↗

Competitive landscape

106 competitors in this universe: 17 direct rivals (same mechanism and indication), 4 same-class, 85 same-indication; 74 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
MT-201: this drugPhase 2Multispecific antibodyTL1A, IL-23 p19
Guselkumab (Tremfya)ApprovedMonoclonal antibodyIL-23 p19
Mirikizumab (Omvoh)ApprovedMonoclonal antibodyIL-23 p19
Risankizumab (Skyrizi)ApprovedMonoclonal antibodyIL-23 p19
Ustekinumab-Stba (Steqeyma)Approved—IL-23 p19, IL-12 p40
Ustekinumab-Ttwe (Pyzchiva)Approved—IL-23 p19, IL-12 p40
AfimkibartPhase 3Monoclonal antibodyTL1A
DuvakitugPhase 3Monoclonal antibodyTL1A
JNJ-78934804Phase 3CombinationIL-23 p19, TNF-alpha
PicankibartPhase 3Monoclonal antibodyIL-23 p19
TulisokibartPhase 3Monoclonal antibodyTL1A
SHR-1139Phase 2Monoclonal antibodyIL-23 p19, IL-36 receptor
SPY002Phase 2Monoclonal antibodyTL1A
SPY003Phase 2Monoclonal antibodyIL-23 p19
SSGJ-627Phase 2Biologic (subtype unspecified)TL1A
XmAb942Phase 1/2Monoclonal antibodyTL1A

…and 91 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (2)
Phase 1Healthy VolunteerRecruiting
Est. primary completion 2026-11-12 · NCT07776782 · CT.gov ↗
What to watch
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Phase 1Healthy VolunteerRecruiting
Est. primary completion 2026-11-24 · NCT07219368 · CT.gov ↗
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2027 (1)
April 2027 (1)
Phase 2Crohn's DiseaseRecruiting
Est. primary completion 2027-04-30 · NCT07113522 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Phase 1 (3)