Asset profile

JNJ-78934804

Combination

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Phase 3underway

Evidence outlook · registrational

Crohn's Disease: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2028-06-12.

Also in development:Ulcerative Colitis · Phase 3

How the evidence outlook works ↗

Competitive landscape

118 competitors in this universe: 32 direct rivals (same mechanism and indication), 8 same-class, 78 same-indication; 62 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
JNJ-78934804: this drugPhase 3CombinationIL-23 p19, TNF-alpha
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha
Adalimumab-Bwwd (Hadlima)Approved—TNF-alpha
Adalimumab-Fkjp (Hulio)Approved—TNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
CT-P13 (Inflectra / Remsima)ApprovedMonoclonal antibodyTNF-alpha
Golimumab (Simponi)ApprovedMonoclonal antibodyTNF-alpha
Guselkumab (Tremfya)ApprovedMonoclonal antibodyIL-23 p19

…and 103 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

6 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (2)
June 2028 (1)
Phase 3Crohn's DiseaseRecruiting
Est. primary completion 2028-06-12 · NCT07577843 · CT.gov ↗
What to watch
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August 2028 (1)
Phase 3Ulcerative ColitisRecruiting
Est. primary completion 2028-08-11 · NCT07577856 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (2)