Asset profile

Midazolam (Nayzilam)

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Epilepsy

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

73 competitors in this universe: 10 direct rivals (same mechanism and indication), 3 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Midazolam (Nayzilam): this drugApprovedSmall moleculeGABA-A receptor, GABA-A receptor (benzodiazepine site)
Clobazam (Onfi)ApprovedSmall moleculeGABA-A receptor
Clobazam (Sympazan)ApprovedSmall moleculeGABA-A receptor (benzodiazepine site)
DiastatApprovedCombinationGABA-A receptor
Diazepam (Valium)ApprovedSmall moleculeGABA-A receptor
Diazepam (Valtoco)ApprovedSmall moleculeGABA-A receptor
GanaxoloneApprovedSmall moleculeGABA-A receptor
Phenobarbital Sodium Injection (Sezaby)ApprovedSmall moleculeGABA-A receptor
StiripentolApprovedSmall moleculeGABA-A receptor
Diazepam (Libervant)Phase 3Small moleculeGABA-A receptor
Staccato AlprazolamPhase 3CombinationGABA-A receptor
KH607Phase 3Small moleculeGABA-A receptor
GlyphAllo (allopregnanolone Prodrug) (SPT-300)Phase 2Small moleculeGABA-A receptor
HS-10353Phase 2Small moleculeGABA-A receptor
BrivaracetamApprovedSmall moleculeSynaptic vesicle glycoprotein 2A (SV2A)
Cannabidiol (Epidiolex)ApprovedSmall moleculeGPR55 / TRPV1 / adenosine transport (multi-target), cannabinoid

…and 58 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

4 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.