Asset profile

RAP-219

Small molecule

Phase 3underway

Evidence outlook · registrational

Epilepsy: registrational readout pending

Entered Phase 3 on weak signal mid-stage evidence. Registrational readout expected around 2029-07.

NCT06377930: The study enrolled 30 participants in a single, open-label RAP-219 group without randomization or a placebo/active comparator, relying on within-participant baseline comparisons for the clinical seizure endpoint. Because no trial results are posted, whether the primary endpoint was met is unknown, and the uncontrolled design provides weak evidence.

How the evidence outlook works ↗

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (1)
February 2028 (1)
Phase 2EpilepsyRecruiting
Est. primary completion 2028-02-03 · NCT07219407 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2029 (2)
July 2029 (2)
Phase 3EpilepsyRecruiting
Est. primary completion 2029-07 · NCT07594119 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 3EpilepsyRecruiting
Est. primary completion 2029-07 · NCT07563881 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

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