Asset profile

Brivaracetam

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Epilepsy

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Competitive landscape

61 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Brivaracetam: this drugApprovedSmall moleculeSynaptic vesicle glycoprotein 2A (SV2A)
Levetiracetam (Elepsia XR)ApprovedSmall moleculeSynaptic vesicle glycoprotein 2A (SV2A)
Cannabidiol (Epidiolex)ApprovedSmall moleculeGPR55 / TRPV1 / adenosine transport (multi-target), cannabinoid
CarbamazepineApprovedSmall moleculeSodium channels
Cenobamate (Xcopri)ApprovedSmall moleculeSodium channels + GABA-A receptors
Clobazam (Onfi)ApprovedSmall moleculeGABA-A receptor
Clobazam (Sympazan)ApprovedSmall moleculeGABA-A receptor (benzodiazepine site)
DiastatApprovedCombinationGABA-A receptor
Diazepam (Valium)ApprovedSmall moleculeGABA-A receptor
Diazepam (Valtoco)ApprovedSmall moleculeGABA-A receptor
Divalproex Sodium (Depakote)ApprovedSmall moleculeGABAergic neurotransmission
Eslicarbazepine Acetate (Aptiom)ApprovedSmall moleculeVoltage-gated sodium channel
EthosuximideApprovedSmall moleculeT-type calcium channel
EverolimusApprovedSmall moleculemTOR kinase, mTOR (mTORC1) (inhibitor)
Ezogabine (Potiga)ApprovedSmall moleculeKv7 potassium channel
FelbamateApprovedSmall moleculeNMDA receptor (glycine site, antagonist)

…and 46 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2029 (2)
June 2029 (1)
Phase 1/2Alzheimer Disease, Mild Cognitive ImpairmentNot yet recruiting
Est. primary completion 2029-06-01 · NCT05899764 · CT.gov ↗
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November 2029 (1)
Phase 3EpilepsyActive not recruiting
Est. primary completion 2029-11-16 · NCT06315322 · CT.gov ↗
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2030 (1)
July 2030 (1)
Phase 3EpilepsyRecruiting
Est. primary completion 2030-07-08 · NCT04715646 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (26)
Phase 2 (8)
Phase 1/2 (2)
Phase 1 (12)
Early phase / not applicable (2)
Appears in other studies (1)