Asset profile

BMB-101

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Dravet Syndrome and Developmental Epileptic EncephalopathiesAbsence Seizures

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 58 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
BMB-101: this drugPhase 2Small moleculeSerotonin 5-HT2C receptor (biased agonist)
BrivaracetamApprovedSmall moleculeSynaptic vesicle glycoprotein 2A (SV2A)
Cannabidiol (Epidiolex)ApprovedSmall moleculeGPR55 / TRPV1 / adenosine transport (multi-target), cannabinoid
CarbamazepineApprovedSmall moleculeSodium channels
Cenobamate (Xcopri)ApprovedSmall moleculeSodium channels + GABA-A receptors
Clobazam (Onfi)ApprovedSmall moleculeGABA-A receptor
Clobazam (Sympazan)ApprovedSmall moleculeGABA-A receptor (benzodiazepine site)
DiastatApprovedCombinationGABA-A receptor
Diazepam (Valium)ApprovedSmall moleculeGABA-A receptor
Diazepam (Valtoco)ApprovedSmall moleculeGABA-A receptor
Divalproex Sodium (Depakote)ApprovedSmall moleculeGABAergic neurotransmission
Eslicarbazepine Acetate (Aptiom)ApprovedSmall moleculeVoltage-gated sodium channel
EthosuximideApprovedSmall moleculeT-type calcium channel
EverolimusApprovedSmall moleculemTOR kinase, mTOR (mTORC1) (inhibitor)
Ezogabine (Potiga)ApprovedSmall moleculeKv7 potassium channel
FelbamateApprovedSmall moleculeNMDA receptor (glycine site, antagonist)

…and 45 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
November 2026 (1)
Phase 2Prader-Willi SyndromeNot yet recruiting
Est. primary completion 2026-11 · NCT07266324 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1 (1)