Asset profile

Ciforadenant

Small molecule

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Multiple Myeloma · Phase 1

How the evidence outlook works ↗

Competitive landscape

64 competitors in this universe: 0 direct rivals (same mechanism and indication), 3 same-class, 61 same-indication; 63 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ciforadenant: this drugPhase 1/2Small moleculeadenosine A2A
Istradefylline (Nourianz)ApprovedSmall moleculeadenosine A2A
VG081821ACPhase 2/3Small moleculeadenosine A2A
TT-10Phase 1/2Small moleculeadenosine A2A
Aldesleukin (Proleukin)ApprovedRecombinant Cytokine (il-2)Interleukin-2 receptor (IL-2R)
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
IxazomibApprovedSmall moleculeProteasome

…and 49 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
November 2026 (1)
Phase 1/2Renal Cell CarcinomaActive not recruiting
Est. primary completion 2026-11-01 · NCT05501054 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 1/2 (3)
Phase 1 (6)