Asset profile

abrocitinib · Cibinqo

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Atopic Dermatitis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

70 competitors in this universe: 6 direct rivals (same mechanism and indication), 4 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Abrocitinib (Cibinqo): this drugApprovedSmall moleculeJAK1
Upadacitinib (Rinvoq)ApprovedSmall moleculeJAK, JAK1
LNK01001Phase 3Small moleculeJAK1
LW402Phase 3Small moleculeJAK1
VC005Phase 3Small moleculeJAK1, JAK1
IN-115314Phase 2Small moleculeJAK1
JYP0061Phase 2Small moleculeJAK1
Filgotinib (Jyseleca)Phase 3Small moleculeJAK, JAK1
AZD4604Phase 2—JAK1
GSK2586184Phase 2Small moleculeJAK1, JAK1
AZD0449Phase 1—JAK1
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Crisaborole (Eucrisa)ApprovedSmall moleculePDE4
Difamilast (Moizerto / Adquey)ApprovedSmall moleculePDE4
Dupilumab (Dupixent)ApprovedMonoclonal antibodyIL-4R-alpha
Lebrikizumab (Ebglyss)ApprovedMonoclonal antibodyIL-13

…and 55 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
October 2026 (1)
Phase 2Diabetes Mellitus, Type 1Active not recruiting
Est. primary completion 2026-10-30 · NCT05743244 · CT.gov ↗
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2027 (3)
March 2027 (1)
Phase 2Atopic DermatitisRecruiting
Est. primary completion 2027-03-01 · NCT07242638 · CT.gov ↗
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May 2027 (2)
Phase 4Atopic DermatitisNot yet recruiting
Est. primary completion 2027-05-01 · NCT07848074 · CT.gov ↗
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Phase 3EczemaRecruiting
Est. primary completion 2027-05-02 · NCT06807268 · CT.gov ↗
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2029 (1)
April 2029 (1)
Phase 3Atopic DermatitisNot yet recruiting
Est. primary completion 2029-04-10 · NCT07823595 · CT.gov ↗
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2030 (1)
June 2030 (1)
Phase 4Atopic DermatitisNot yet recruiting
Est. primary completion 2030-06-01 · NCT07352566 · CT.gov ↗
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2032 (1)
February 2032 (1)
Phase 3Atopic DermatitisRecruiting
Est. primary completion 2032-02-22 · NCT06807281 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (11)
Phase 2 (10)
Phase 1 (20)
Phase 4 (3)