Asset profile

CMS-D001

Small molecule

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Phase 3underway

Evidence outlook · registrational

Psoriasis: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2028-02-29.

Also in development:Atopic Dermatitis · Phase 2

How the evidence outlook works ↗

Competitive landscape

124 competitors in this universe: 10 direct rivals (same mechanism and indication), 2 same-class, 112 same-indication; 77 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
CMS-D001: this drugPhase 2/3Small moleculeTYK2
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
EnvudeucitinibPhase 3Small moleculeTYK2
HS-10374Phase 3Small moleculeTYK2
ICP-488Phase 3Small moleculeTYK2
SYHX1901Phase 3Small moleculeTYK2
TQH3906Phase 3Small moleculeTYK2
WD-890Phase 3Small moleculeTYK2
ZasocitinibPhase 3Small moleculeTYK2
BMS-986322Phase 2Small moleculeTYK2
CS32582Phase 1/2Small moleculeTYK2
D-2570Phase 3Small moleculeTYK2
GLPG3667Phase 2Small moleculeTYK2
Abrocitinib (Cibinqo)ApprovedSmall moleculeJAK1
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Apremilast (Otezla)ApprovedSmall moleculePDE4

…and 109 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

1 further head-to-head pair is tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
January 2027 (1)
Phase 2Atopic DermatitisNot yet recruiting
Est. primary completion 2027-01-31 · NCT07465120 · CT.gov ↗
What to watch
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2028 (1)
February 2028 (1)
Phase 2/3PsoriasisNot yet recruiting
Est. primary completion 2028-02-29 · NCT07432854 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2/3 (1)
Phase 2 (1)