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nemolizumab · Nemluvio

Monoclonal antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Atopic Dermatitis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Nemolizumab (Nemluvio): this drugApprovedMonoclonal antibodyIL-31 receptor A
Abrocitinib (Cibinqo)ApprovedSmall moleculeJAK1
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Crisaborole (Eucrisa)ApprovedSmall moleculePDE4
Difamilast (Moizerto / Adquey)ApprovedSmall moleculePDE4
Dupilumab (Dupixent)ApprovedMonoclonal antibodyIL-4R-alpha
Lebrikizumab (Ebglyss)ApprovedMonoclonal antibodyIL-13
Roflumilast (Zoryve)ApprovedSmall moleculePDE4
RuxolitinibApprovedSmall moleculeJAK1/2
TapinarofApprovedSmall moleculeAryl hydrocarbon receptor, Aryl Hydrocarbon Receptor Agonist
Tralokinumab (Adbry)ApprovedMonoclonal antibodyIL-13
Upadacitinib (Rinvoq)ApprovedSmall moleculeJAK, JAK1
ADSTEMPhase 3Cell therapyautologous adipose-derived mesenchymal stem cell (AD-MSC) therapy
AfimkibartPhase 3Monoclonal antibodyTL1A
AsivatrepPhase 3Small moleculeTRPV1
BarzolvolimabPhase 3Monoclonal antibodyKIT

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
October 2026 (1)
Phase 3Prurigo NodularisActive not recruiting
Est. primary completion 2026-10-26 · NCT04204616 · CT.gov ↗
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December 2026 (1)
Phase 2Chronic Pruritus of Unknown OriginActive not recruiting
Est. primary completion 2026-12 · NCT07074977 · CT.gov ↗
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2027 (3)
June 2027 (1)
Phase 4Lichen Plano-PilarisRecruiting
Est. primary completion 2027-06 · NCT07396168 · CT.gov ↗
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September 2027 (2)
Phase 2Lichen Sclerosus of VulvaNot yet recruiting
Est. primary completion 2027-09-01 · NCT07704775 · CT.gov ↗
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Phase 3Atopic DermatitisNot yet recruiting
Est. primary completion 2027-09-28 · NCT07762833 · CT.gov ↗
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2028 (2)
May 2028 (1)
Phase 2Systemic SclerosisRecruiting
Est. primary completion 2028-05-28 · NCT07047690 · CT.gov ↗
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July 2028 (1)
Phase 2Atopic DermatitisRecruiting
Est. primary completion 2028-07-15 · NCT07660835 · CT.gov ↗
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2030 (1)
June 2030 (1)
Phase 4Atopic DermatitisNot yet recruiting
Est. primary completion 2030-06-01 · NCT07352566 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (9)
Phase 2/3 (1)
Phase 2 (12)
Phase 1 (1)
Phase 4 (2)