Asset profile

ADSTEM

Cell therapy

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Phase 3underway

Evidence outlook · registrational

Atopic Dermatitis: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2029-06.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 12 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
ADSTEM: this drugPhase 3Cell therapyautologous adipose-derived mesenchymal stem cell (AD-MSC) therapy
Abrocitinib (Cibinqo)ApprovedSmall moleculeJAK1
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Crisaborole (Eucrisa)ApprovedSmall moleculePDE4
Difamilast (Moizerto / Adquey)ApprovedSmall moleculePDE4
Dupilumab (Dupixent)ApprovedMonoclonal antibodyIL-4R-alpha
Lebrikizumab (Ebglyss)ApprovedMonoclonal antibodyIL-13
Nemolizumab (Nemluvio)ApprovedMonoclonal antibodyIL-31 receptor A
Roflumilast (Zoryve)ApprovedSmall moleculePDE4
RuxolitinibApprovedSmall moleculeJAK1/2
TapinarofApprovedSmall moleculeAryl hydrocarbon receptor, Aryl Hydrocarbon Receptor Agonist
Tralokinumab (Adbry)ApprovedMonoclonal antibodyIL-13
Upadacitinib (Rinvoq)ApprovedSmall moleculeJAK, JAK1
AfimkibartPhase 3Monoclonal antibodyTL1A
AsivatrepPhase 3Small moleculeTRPV1
BarzolvolimabPhase 3Monoclonal antibodyKIT

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
December 2027 (1)
Phase 2/3Osteoarthritis KneeEnrolling by invitation
Est. primary completion 2027-12 · NCT06893250 · CT.gov ↗
What to watch
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2029 (1)
June 2029 (1)
Phase 3Atopic DermatitisNot yet recruiting
Est. primary completion 2029-06 · NCT07377838 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2/3 (1)
Phase 2 (1)
Phase 1 (1)