Asset profile

QL2108

Monoclonal antibody

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Phase 3underway

Evidence outlook · registrational

Atopic Dermatitis: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-05.

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Competitive landscape

66 competitors in this universe: 6 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 12 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
QL2108: this drugPhase 3Monoclonal antibodyIL-4R-alpha
Dupilumab (Dupixent)ApprovedMonoclonal antibodyIL-4R-alpha
GS101Phase 3Monoclonal antibodyIL-4R-alpha
ManfidokimabPhase 3Monoclonal antibodyIL-4R-alpha
RademikibartPhase 3Monoclonal antibodyIL-4R-alpha
StapokibartPhase 3Monoclonal antibodyIL-4R-alpha
CKD-706Phase 1Monoclonal antibodyIL-4R-alpha
Abrocitinib (Cibinqo)ApprovedSmall moleculeJAK1
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Crisaborole (Eucrisa)ApprovedSmall moleculePDE4
Difamilast (Moizerto / Adquey)ApprovedSmall moleculePDE4
Lebrikizumab (Ebglyss)ApprovedMonoclonal antibodyIL-13
Nemolizumab (Nemluvio)ApprovedMonoclonal antibodyIL-31 receptor A
Roflumilast (Zoryve)ApprovedSmall moleculePDE4
RuxolitinibApprovedSmall moleculeJAK1/2
TapinarofApprovedSmall moleculeAryl hydrocarbon receptor, Aryl Hydrocarbon Receptor Agonist

…and 51 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
May 2027 (1)
Phase 3Atopic DermatitisNot yet recruiting
Est. primary completion 2027-05 · NCT06884891 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.