Asset profile

HS-10374

Small molecule

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Phase 3underway

Evidence outlook · registrational

Psoriasis: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. The registry's posted readout date (2025-10-22) has passed without a status update. Check News for topline announcements.

Also in development:Psoriatic Arthritis · Phase 2

How the evidence outlook works ↗

Competitive landscape

92 competitors in this universe: 10 direct rivals (same mechanism and indication), 2 same-class, 80 same-indication; 48 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
HS-10374: this drugPhase 3Small moleculeTYK2
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
EnvudeucitinibPhase 3Small moleculeTYK2
ICP-488Phase 3Small moleculeTYK2
SYHX1901Phase 3Small moleculeTYK2
TQH3906Phase 3Small moleculeTYK2
WD-890Phase 3Small moleculeTYK2
ZasocitinibPhase 3Small moleculeTYK2
CMS-D001Phase 2/3Small moleculeTYK2
BMS-986322Phase 2Small moleculeTYK2
CS32582Phase 1/2Small moleculeTYK2
D-2570Phase 3Small moleculeTYK2
GLPG3667Phase 2Small moleculeTYK2
Abatacept (Orencia)ApprovedProtein / enzyme therapeuticCD80/CD86 (CTLA-4-Ig), Selective T Cell Costimulation Modulator, CD80/CD86 (B7-1/B7-2) on antigen-presenting cells
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha

…and 77 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

1 further head-to-head pair is tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (3)
Phase 1 (2)