Asset profile

Calcipotriene/Betamethasone Dipropionate Foam · Enstilar

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Psoriasis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

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Competitive landscape

61 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Calcipotriene / Betamethasone Dipropionate Foam (Enstilar): this drugApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Calcipotriene / Betamethasone Dipropionate Cream (Wynzora)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Apremilast (Otezla)ApprovedSmall moleculePDE4
Bimekizumab (Bimzelx)ApprovedMonoclonal antibodyIL-17A/F
Brepocitinib (Lisraya)ApprovedSmall moleculeTYK2/JAK1
Brodalumab (Siliq)ApprovedMonoclonal antibodyIL-17 receptor A
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
Desoximetasone (Topicort Spray)ApprovedSmall moleculeGlucocorticoid receptor agonist
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Guselkumab (Tremfya)ApprovedMonoclonal antibodyIL-23 p19
Halobetasol Propionate Foam (Lexette)ApprovedSmall moleculeGlucocorticoid receptor
Halobetasol Propionate Lotion (Bryhali)ApprovedSmall moleculeGlucocorticoid receptor
Halobetasol Propionate / Tazarotene (Duobrii)ApprovedSmall moleculeGlucocorticoid receptor + retinoic acid receptor
IcotrokinraApprovedPeptideIL-23 receptor

…and 46 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (1)
Phase 4 (10)
Appears in other studies (4)