Asset profile

ENS-002

Microbiome therapeutic

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Stoppedregistry status

Evidence outlook

Development stopped: Phase 1 study terminated

The drug's registered studies are all terminated, withdrawn or suspended (NCT06469385: terminated); none completed, so no evidence signal is assigned. Check the registry record for the sponsor's stated reason.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 60 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
ENS-002: this drugPhase 1Microbiome therapeutictopical live biotherapeutic product (three-strain bacterial consortium)
Abrocitinib (Cibinqo)ApprovedSmall moleculeJAK1
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Crisaborole (Eucrisa)ApprovedSmall moleculePDE4
Difamilast (Moizerto / Adquey)ApprovedSmall moleculePDE4
Dupilumab (Dupixent)ApprovedMonoclonal antibodyIL-4R-alpha
Lebrikizumab (Ebglyss)ApprovedMonoclonal antibodyIL-13
Nemolizumab (Nemluvio)ApprovedMonoclonal antibodyIL-31 receptor A
Roflumilast (Zoryve)ApprovedSmall moleculePDE4
RuxolitinibApprovedSmall moleculeJAK1/2
TapinarofApprovedSmall moleculeAryl hydrocarbon receptor, Aryl Hydrocarbon Receptor Agonist
Tralokinumab (Adbry)ApprovedMonoclonal antibodyIL-13
Upadacitinib (Rinvoq)ApprovedSmall moleculeJAK, JAK1
ADSTEMPhase 3Cell therapyautologous adipose-derived mesenchymal stem cell (AD-MSC) therapy
AfimkibartPhase 3Monoclonal antibodyTL1A
AsivatrepPhase 3Small moleculeTRPV1

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.