Asset profile

sitokiren

Small molecule

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Phase 3underway

Evidence outlook · registrational

Hypertension: registrational trials complete, results ungraded

Its supporting mid-stage evidence has not yet been graded on this platform. Its registrational studies have completed; results have not been graded on this platform. Check News and the registry record for topline outcomes.

Also in development:Ulcerative Colitis · Phase 2

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Competitive landscape

120 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 120 same-indication; 61 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Sitokiren: this drugPhase 3Small moleculeRenin
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha
Adalimumab-Bwwd (Hadlima)Approved—TNF-alpha
Adalimumab-Fkjp (Hulio)Approved—TNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Aprocitentan (Tryvio)ApprovedSmall moleculeEndothelin receptor (ETA/ETB, dual)
Balsalazide Disodium (Colazal)Approved—Aminosalicylate
Balsalazide Disodium (Giazo)Approved—Aminosalicylate
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)

…and 105 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (4)
Phase 1/2 (2)
Phase 1 (3)