Asset profile

etrasimod · Velsipity

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Ulcerative Colitis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

67 competitors in this universe: 3 direct rivals (same mechanism and indication), 4 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Etrasimod (Velsipity): this drugApprovedSmall moleculeS1P receptor
Ozanimod (Zeposia)ApprovedSmall moleculeS1P receptor
AmiselimodPhase 2Small moleculeS1P receptor
TamuzimodPhase 2Small moleculeS1P receptor
Fingolimod (Gilenya)ApprovedSmall moleculeSphingosine 1-phosphate receptor (S1PR, specifically S1P1), S1P receptor, Sphingosine-1-phosphate receptors (S1P1, S1P3, S1P4, S1P5)
MayzentApprovedSmall moleculeS1P receptor
PonesimodApprovedSmall moleculeS1P receptor
Tascenso ODTApprovedSmall moleculeS1P receptor
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha

…and 52 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(6 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
June 2027 (1)
Phase 4Ulcerative ColitisNot yet recruiting
Est. primary completion 2027-06-30 · NCT07782242 · CT.gov ↗
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September 2027 (1)
Early phase / not applicableUlcerative ColitisRecruiting
Est. primary completion 2027-09-30 · NCT07243639 · CT.gov ↗
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2029 (2)
June 2029 (2)
Phase 2Ulcerative ColitisRecruiting
Est. primary completion 2029-06-16 · NCT05287126 · CT.gov ↗
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Phase 3Ulcerative ColitisActive not recruiting
Est. primary completion 2029-06-19 · NCT03950232 · CT.gov ↗
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2030 (2)
February 2030 (1)
Phase 2PouchitisRecruiting
Est. primary completion 2030-02-06 · NCT07486921 · CT.gov ↗
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September 2030 (1)
Phase 2Ulcerative ColitisRecruiting
Est. primary completion 2030-09-08 · NCT07470879 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (5)
Phase 2/3 (2)
Phase 2 (14)
Phase 1 (3)
Phase 4 (1)
Early phase / not applicable (1)
Appears in other studies (1)