Asset profile

tofacitinib · Xeljanz

Small molecule

Approvedregulatory verdict

Evidence outlook

Approved — Rheumatoid Arthritis, Rheumatoid Arthritis, Ulcerative Colitis

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

Also in development:Atopic Dermatitis · Phase 2

How the evidence outlook works ↗

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
September 2026 (1)
Phase 3Rheumatoid ArthritisActive not recruiting
Est. primary completion 2026-09-30 · NCT07008846 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (3)
January 2027 (1)
Phase 2Nail PsoriasisNot yet recruiting
Est. primary completion 2027-01 · NCT07313072 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

March 2027 (1)
Phase 3Ulcerative ColitisActive not recruiting
Est. primary completion 2027-03-17 · NCT04624230 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

May 2027 (1)
Phase 2Ulcerative ColitisNot yet recruiting
Est. primary completion 2027-05-31 · NCT07297069 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (3)
January 2028 (1)
Phase 2Rheumatic DiseaseRecruiting
Est. primary completion 2028-01 · NCT07138898 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

March 2028 (1)
Phase 3Rheumatoid ArthritisRecruiting
Est. primary completion 2028-03 · NCT03414502 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2028 (1)
Phase 3Palmoplantar Pustulosis (PPP)Not yet recruiting
Est. primary completion 2028-08-01 · NCT07530367 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2030 (1)
December 2030 (1)
Phase 2Sjogren's SyndromeRecruiting
Est. primary completion 2030-12-15 · NCT07281456 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

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Competitive landscape

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