Asset profile

ozanimod · Zeposia

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Multiple Sclerosis, Ulcerative Colitis (label: moderately to severely active UC who have had an inadequate response, lost response, or were...)

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

107 competitors in this universe: 7 direct rivals (same mechanism and indication), 0 same-class, 100 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ozanimod (Zeposia): this drugApprovedSmall moleculeS1P receptor
Etrasimod (Velsipity)ApprovedSmall moleculeS1P receptor
Fingolimod (Gilenya)ApprovedSmall moleculeSphingosine 1-phosphate receptor (S1PR, specifically S1P1), S1P receptor, Sphingosine-1-phosphate receptors (S1P1, S1P3, S1P4, S1P5)
MayzentApprovedSmall moleculeS1P receptor
PonesimodApprovedSmall moleculeS1P receptor
Tascenso ODTApprovedSmall moleculeS1P receptor
AmiselimodPhase 2Small moleculeS1P receptor
TamuzimodPhase 2Small moleculeS1P receptor
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha

…and 92 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

1 further head-to-head pair is tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(5 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
June 2027 (1)
Phase 2Alzheimer DiseaseRecruiting
Est. primary completion 2027-06-30 · NCT06862960 · CT.gov ↗
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2028 (2)
August 2028 (1)
Phase 4Multiple SclerosisRecruiting
Est. primary completion 2028-08-01 · NCT06529406 · CT.gov ↗
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December 2028 (1)
Phase 4Multiple SclerosisActive not recruiting
Est. primary completion 2028-12-29 · NCT06396039 · CT.gov ↗
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2031 (1)
April 2031 (1)
Phase 3Multiple SclerosisRecruiting
Est. primary completion 2031-04-11 · NCT06408259 · CT.gov ↗
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2032 (1)
July 2032 (1)
Phase 2/3Ulcerative ColitisRecruiting
Est. primary completion 2032-07-12 · NCT05076175 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (13)
Phase 2/3 (3)
Phase 2 (4)
Phase 1 (11)
Phase 4 (7)
Early phase / not applicable (1)
Appears in other studies (1)