Asset profile

Ofatumumab

Monoclonal antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Multiple Sclerosis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

51 competitors in this universe: 8 direct rivals (same mechanism and indication), 7 same-class, 36 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ofatumumab: this drugApprovedMonoclonal antibodyCD20
OcrelizumabApprovedMonoclonal antibodyCD20
Ocrevus ZunovoApprovedMonoclonal antibodyCD20
UblituximabApprovedMonoclonal antibodyCD20
ABP 692Phase 3Monoclonal antibodyCD20
BCD-132Phase 3Monoclonal antibodyCD20
BCD-281Phase 3Monoclonal antibodyCD20
CT-P53Phase 3Monoclonal antibodyCD20
DivozilimabPhase 3Monoclonal antibodyCD20
PF-05280586ApprovedBiologic (subtype unspecified)CD20
RituximabApprovedMonoclonal antibodyCD20, CD20-directed Cytolytic Antibody
AcellbiaPhase 3Monoclonal antibodyCD20
CT-P10Phase 3Monoclonal antibodyCD20
HLX01Phase 3Monoclonal antibodyCD20
MIL62Phase 3Monoclonal antibodyCD20
SAR448501Phase 1Multispecific antibodyCD20

…and 36 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

2 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(6 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (2)
Phase 2B Acute Lymphoblastic Leukemia, B Lymphoblastic LymphomaRecruiting
Est. primary completion 2026-11-01 · NCT02877303 · CT.gov ↗
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Phase 3Anti-N-Methyl-D-Aspartate Receptor EncephalitisRecruiting
Est. primary completion 2026-11-08 · NCT06867991 · CT.gov ↗
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2027 (3)
April 2027 (1)
Phase 4Multiple SclerosisActive not recruiting
Est. primary completion 2027-04-13 · NCT05090371 · CT.gov ↗
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August 2027 (1)
Phase 2Recurrent Acute Lymphoblastic Leukemia, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Burkitt Leukemia, Recurrent Burkitt Lymphoma …Recruiting
Est. primary completion 2027-08-01 · NCT03136146 · CT.gov ↗
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December 2027 (1)
Phase 1Multiple SclerosisNot yet recruiting
Est. primary completion 2027-12-30 · NCT07546110 · CT.gov ↗
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2028 (1)
September 2028 (1)
Phase 3Multiple SclerosisActive not recruiting
Est. primary completion 2028-09-30 · NCT03650114 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (23)
Phase 2 (78)
Phase 1/2 (9)
Phase 1 (9)
Phase 4 (8)
Early phase / not applicable (1)
Used as active comparator (5)