Asset profile

Ocrelizumab

Monoclonal antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Multiple Sclerosis

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

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Competitive landscape

51 competitors in this universe: 8 direct rivals (same mechanism and indication), 7 same-class, 36 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ocrelizumab: this drugApprovedMonoclonal antibodyCD20
Ocrevus ZunovoApprovedMonoclonal antibodyCD20
OfatumumabApprovedMonoclonal antibodyCD20
UblituximabApprovedMonoclonal antibodyCD20
ABP 692Phase 3Monoclonal antibodyCD20
BCD-132Phase 3Monoclonal antibodyCD20
BCD-281Phase 3Monoclonal antibodyCD20
CT-P53Phase 3Monoclonal antibodyCD20
DivozilimabPhase 3Monoclonal antibodyCD20
PF-05280586ApprovedBiologic (subtype unspecified)CD20
RituximabApprovedMonoclonal antibodyCD20, CD20-directed Cytolytic Antibody
AcellbiaPhase 3Monoclonal antibodyCD20
CT-P10Phase 3Monoclonal antibodyCD20
HLX01Phase 3Monoclonal antibodyCD20
MIL62Phase 3Monoclonal antibodyCD20
SAR448501Phase 1Multispecific antibodyCD20

…and 36 more. Research shows the complete landscape.

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Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

2 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

(16 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (3)
October 2026 (1)
Phase 3Multiple SclerosisActive not recruiting
Est. primary completion 2026-10-22 · NCT03523858 · CT.gov ↗
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November 2026 (1)
Phase 3Multiple SclerosisActive not recruiting
Est. primary completion 2026-11 · NCT06847724 · CT.gov ↗
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December 2026 (1)
Phase 4Multiple SclerosisActive not recruiting
Est. primary completion 2026-12 · NCT04466150 · CT.gov ↗
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2027 (4)
February 2027 (1)
Phase 4Multiple SclerosisActive not recruiting
Est. primary completion 2027-02 · NCT05296161 · CT.gov ↗
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June 2027 (1)
Phase 4Multiple SclerosisEnrolling by invitation
Est. primary completion 2027-06-30 · NCT06495593 · CT.gov ↗
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December 2027 (2)
Phase 3Multiple SclerosisActive not recruiting
Est. primary completion 2027-12-31 · NCT05269004 · CT.gov ↗
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Phase 4Multiple SclerosisActive not recruiting
Est. primary completion 2027-12-31 · NCT07483450 · CT.gov ↗
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2028 (5)
February 2028 (1)
Phase 1Multiple SclerosisActive not recruiting
Est. primary completion 2028-02-15 · NCT07667322 · CT.gov ↗
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May 2028 (2)
Phase 3Multiple SclerosisActive not recruiting
Est. primary completion 2028-05 · NCT05999604 · CT.gov ↗
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Phase 2Multiple SclerosisRecruiting
Est. primary completion 2028-05-30 · NCT07282574 · CT.gov ↗
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June 2028 (2)
Early phase / not applicableMultiple SclerosisNot yet recruiting
Est. primary completion 2028-06-01 · NCT07181811 · CT.gov ↗
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Phase 1/2Schizo-Affective Type of Psychosis, SchizophreniaRecruiting
Est. primary completion 2028-06-30 · NCT03971487 · CT.gov ↗
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2029 (3)
February 2029 (1)
Phase 4Multiple SclerosisRecruiting
Est. primary completion 2029-02-28 · NCT07609719 · CT.gov ↗
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August 2029 (1)
Phase 3Multiple SclerosisNot yet recruiting
Est. primary completion 2029-08-01 · NCT07503340 · CT.gov ↗
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December 2029 (1)
Phase 3Multiple SclerosisRecruiting
Est. primary completion 2029-12-31 · NCT06675955 · CT.gov ↗
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2031 (1)
August 2031 (1)
Phase 4Multiple SclerosisActive not recruiting
Est. primary completion 2031-08-25 · NCT05285891 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (30)
Phase 2 (7)
Phase 1/2 (4)
Phase 1 (3)
Phase 4 (15)
Early phase / not applicable (3)
Used as active comparator (11)
Appears in other studies (6)